DocumentsDate added
Original article
Moulshree Kohli1,Puneet Ahuja2, Amit Gupta3*
1 Post graduate student, Department of Oral and Maxillofacial Pathology and Microbiology, I.T.S. Dental College, Hospital and Research Centre, Greater Noida, Uttar Pradesh, India
2 Prof & Head, Department of Oral and Maxillofacial Pathology and Microbiology, I.T.S. Dental College, Hospital and Research Centre, Greater Noida, Uttar Pradesh, India
3Senior Lecturer, Department of Oral and Maxillofacial Pathology and Microbiology, I.T.S. Dental College, Hospital and Research Centre, Greater Noida, Uttar Pradesh, India
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*Dr. Amit Gupta,
Department of Oral and Maxillofacial Pathology and Microbiology, ITS Dental College, Hospital and Research Centre, Greater Noida, Uttar Pradesh, India
Article citation: Kohli M, Ahuja P, Gupta A. EVALUATION OF DIFFERENT DECALCIFYING AGENTS ON ORAL HARD TISSUES:A COMPARATIVE STUDY.J Pharm Biomed Sci 2015;05(10):804–806. Available at www.jpbms.info
Introduction Decalcification of bone and teeth is often an essential and important step during tissue processing. The rate of decalcification and the effect of various decalcifying agents on the tissue and their staining characteristics are two important parameters influencing the selection of decalcifying solutions. Some decalcifying agents, although they completely and rapidly remove the calcium ions also adversely affect the staining characteristics and may cause damage to the organic components. This study aimed to EVALUATE the efficacy of the commonly used demineralizing agents to identify the best decalcifying agent. Materials and Methods Three decalcifying agents namely, 10 percent nitric acid, 10 percent hydrochloric acid and 10 percent formic acid were used to decalcify 30 natural teeth.The endpoint of decalcification was EVALUATED by physical and chemical methods. The decalcified teeth were subjected to routine processing and staining with hematoxylin and eosin stains.
Result Formic acid of 10% was the most considerate to the hard tissues and 10% hydrochloric acid was the least considerate to the tooth structure.
Conclusion Formic acid of 10% though being the slowest decalcifying agent, gave excellent results for soft-tissue integrity and staining characteristics.
KEYWORDS 10% nitric acid, 10% hydrochloric acid, 10% formic acid, decalcifying agents
Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None.
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Original article
Loudjedi Salim1*, Bereksi Amian1, Khemis Kamila2, Dib Fadel3, Toaba Toaba1,
Taouagh Nacereddine1, Kherbouche Mouffok1
1 Hospital of Tlemcen, Department of Medicine, University of Tlemcen, Algeria
2 Department of GBM, University of Tlemcen, Algeria
3 Hospital of Tlemcen Gastroenterology,Department of Medicine, University of Tlemcen, Algeria
Address reprint requests to
*Dr. Loudjedi Salim,
Hospital of Tlemcen,
Department of Medicine, University of Tlemcen, Algeria
Article citation: Salim L, Amian B, Kamila K, Fadel D, Toaba T, Nacereddine T, Mouffok K. Evidence-based medicine in biliary surgery: a model of applicability. J Pharm Biomed Sci 2015;05(10):807–811.Available at www.jpbms.info
Abstract:
Background Evidence-based medicine (EBM) is the conscientious and judicious use of the best data in the literature for optimal care of patients. This must go through four steps: (1) formulation of a clear clinical question, (2) research documented facts, (3) analysis of results and (4) application of results in clinical practice.
Methods Our choice of application was gallstones and complications because it is a frequent and complex pathology that requires several clinical questions. The experimental design was considered to be a non-comparative cohort study (patients were exposed to evidence-based medicine). It can also be considered as a feasibility study. In our application we took the following steps: (1) formulation of several clinical questions, (2) literature search in medline using MeSH and Cochrane library, (3) analysis of results through critical reading of collected articles, (4) calculation of percentage of patients for each clinical situation and correlating it with the levels of evidence. Then we estimated the matching of our application with EBM by calculating the number of positive responses.
Conclusion As a conclusion we were able to apply EBM with some degrees of confidence.
However, some limitations related to environmental factors are still present. We can overcome this problem by introducing an educational learning model.
KEYWORDS EVIDENCE-based medicine, gallstones, non-comparative, cohort, education
Source of funding: None.
Competing interest / Conflict of interest:
The author(s) have no competing interests for financial support, publication of this research, patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Case Report
Ambarisha Bhandiwad1, Surakshith L. Gowda2*
1Professor and Head, Department of OBG,JSS Medical College, JSS University,Mysore, Karnataka, India
2Junior Resident, Department of OBG, JSS Medical College, JSS University, Mysore,Karnataka, India
Address reprint requests to
*Dr. Surakshith L. Gowda,
No. 140/4, 2nd Cross, Shankarmutt road, Fort Mohalla,Mysore 570004, Karnataka, India
Article citation: Bhandiwad A, Gowda SL.Hepatitis E in pregnancy: a case report.J Pharm Biomed Sci 2015;05(10):797–798.Available at www.jpbms.info
ABSTRACT Viral hepatitis is one of the most common infectious diseases in developing countries. Hepatitis E in particular has a wide geographical variation and it either occur
as epidemics or seen as sporadic cases. Mainly when pregnant women are affected with Hepatitis E, the disease will be more severe if the women is in second or third trimester,
particularly in third trimester, where chances of fulminant hepatic failure is more with high mortality rates. Here we are presenting a case of acute viral hepatitis complicating pregnancy
where the women goes into spontaneous labour and almost ends in postpartum hemorrhage. Due to timely intervention by transfusing blood components the possible
harm was prevented. Each patient can behave in different way so the plan of management should be tailor made to each patient.
KEYWORDS Viral hepatitis, hepatitis E, pregnancy, fulminant hepatic failure, postpartum haemorrhage, component therapy
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Source of funding: None.
Competing interest / Conflict of interest:
The author(s) have no competing interests for financial support, publication of this research, patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Case Report
Kushal Baidya1, Abdul Wahid Khan1, Ajaz Suhaff1, Asma Manjoor1, Umar Majid2*
1 Department of Psychiatry, SKIMS Medical College and Hospital, Bemina, Srinagar, Kashmir India
2 Department of Pulmonary and Critical Care Medicine, SKIMS MC Hospital, Bemina, Srinagar, India
Address reprint requests to
*Dr. M Umar Majid,
Department of Pulmonary and Critical Care Medicine, SKIMS MC and Hospital Bemina,
Srinagar KMR, India.
Article citation: Baidya K, Khan AW, Suhaff A, Manjoor A, Majid U. Phobia with hallucinations in a patient with implantable cardioverter defibrillator: a case report. J Pharm Biomed Sci 2015;05(10):771–773.
ABSTRACT This case report describes a 21-year-old patient with implantable cardioverter defibrillator (ICD) diagnosed as phobia with prominent visual hallucinations which were incapacitating. He was treated with sertraline 200 mg/d and clonazepam 0.5 mg/d for 1 month after which his symptoms resolved. It was emphasized that patients with ICD are prone to develop psychiatric disorder and require special attention. Visual hallucinations developed may be present across different spectrum of disorders. Treating the underlying condition resolves hallucinations occurring without psychotic features.
KEYWORDS: visual hallucinations, phobia, anxiety disorder, ICD
Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None.
Competing interest / Conflict of interest:
The author(s) have no competing interests for financial support, publication of this research, patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Case Report
Mahendra Wawhal1,Vajed Mogal2*,Sandeep Sanap3,Atul Jadhav4
1 Associate Professor and Consultant,2,3 Senior Resident, 4Junior Resident Department of Medicine, MGM Medical College and Hospital, Aurangabad431003, Maharashtra, India
Address reprint requests to
*Dr. Vajed Mogal, Senior Resident,
Department of Medicine, M.G.M. Medical college and Hospital, Aurangabad 431003, Maharashtra, India
Article citation: Wawhal M, Mogal V,Sanap S, Jadhav A. Post-streptococcal reactive arthritis: a rare case report and a brief review of literature. J Pharm Biomed Sci 2015;05(10):774–776.Available at www.jpbms.info
ABSTRACT: We report the case of a 30-year-old woman who developed severe post-streptococcal reactive arthritis (PSRA) after a subclinical streptococcal infection. Anti-streptococcal antibody titres and clinical course confirmed the diagnosis. Coincidence of PSRA is rare in the adult population and the potential for misdiagnosis exists, particularly when prior streptococcal infection is not apparent. The clinical manifestations of post-streptococcal syndromes are highly variable, and the diagnosis of concomitant PSRA should be considered when patients present with inflammatory arthritis. Factors from both the host and the pathogen are probably important in determining disease expression in post-streptococcal syndromes.
KEYWORDS: post-streptococcal reactive arthritis, streptococcal infection
Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None.
Competing interest / Conflict of interest:
The author(s) have no competing interests for financial support, publication of this research, patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.