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Name | Synthesis and Biological Activities of Some New 2-S-Substituted Aminomethylthio-3-Aryl-4(3H) Quinazolinones. |
Description | Original research article:- *Damerakonda Kumaraswamy1,Vanga mallareddy2 1.Department of Pharmaceutical Chemistry,Vaagdevi College of Pharmacy,Hanamkonda,Warangal, Andhrapradesh,India. 2.Department of Medicinal Chemistry, Devis lab,Research and Development unit,Hyderabad, Andhrapradesh. India.
Abstract:-The Mannich reaction on 3-Aryl-3,4-di hydro-4-oxoquinazolin-2-thione with different secondary amines yielded asingle product in each case.The mannich bases obtained have been characterized as the corresponding 2-S-substituted amino methyl thio-3-aryl 4(3H) quinazolinone(VI) on the basis of analytical spectral data.These S-Substituted compounds have been screened for their Anti- bacterial,Anti -fungal,Anti- inflammatory and Analgesic activities. |
Filename | Kumaraswamy D et.al..pdf |
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Created On: | 04/17/2011 00:00 |
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Last updated on | 04/27/2011 15:33 |
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