Property | Value |
Name | Development and Evaluation of Liposomes of Fluconazole |
Description | Original research article:- *Harika Chanda1 Palash Das1, Rahul Chakraborty 2, Arpita Ghosh 3 *1,2.Department of Pharmaceutics, MLR Institute of Pharmacy, Hyderabad, India. 1.Department of Pharmaceutics, Sri Krupa college of Pharmacy, Siddipet, India. 3.Department of Pharmaceutics, Vikas college of Pharmacy, Jangaon, India.
Abstract Aims:-The purpose of research involves to prepare the liposomes of anti fungal drug, fluconazole which were encapsulated in the form of liposomes for topical application and to improve the therapeutic response and reduce the possible adverse symptoms. Here liposomes of Fluconazole were prepared by thin film hydration technique using soya lecithin, cholesterol and drug in different weight ratios. The prepared liposomes were characterized for size, shape, entrapment efficiency, in-vitro drug release (by franz diffusion cell) and physical stability. The studies demonstrated successful preparation of Fluconazole liposomes and effect of soya lecithin: cholesterol weight ratio on entrapment efficiency and on drug release.
Keywords: Antifungal, liposomes, fluconazole, soya lecithin, cholesterol. |
Filename | Chanda H et.al..pdf |
Filesize | 460.78 kB |
Filetype | pdf (Mime Type: application/pdf) |
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Created On: | 04/18/2011 00:00 |
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Last updated on | 05/05/2011 07:03 |
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