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Name | Relationship between obesity and Immunoglobulin E in bronchial asthma subjects |
Description | Research article:-A. G. Rajalakshmi 1, J.Unnithan2, *S. Sudha 1 1.Department of Biotechnology, Karpagam University, Coimbatore 641021, Tamil Nadu, India. 2.Department of Pulmonology, Kovai Respiratory Care and Research Centre, Coimbatore 641002, Tamil Nadu, India.
Abstract:-The occurrence of both obesity and asthma has increased among people over the last several decades. Former data on the association between obesity and asthma has been inconsistent. This study aimed to examine the association of obesity with total IgE levels in south Indian asthma subjects. The serum IgE level was examined in 75 asthma patients and their severities of asthma were determined by pulmonary function tests. Serum IgE level was compared with the severity of asthma and Body Mass Index. Total serum IgE levels significantly increased in obese and asthma groups when compared to control subjects (p<0.005). The data indicated a significant positive correlation between IgE levels and body mass index (BMI) in asthmatic patients (mild P<0.009, moderate P<0.021 and severe asthma P<0.010). The present study suggests that the serum IgE level may reproduce the severity of bronchial asthma. The evidence for the relationship between obesity and asthma is not conclusive however the study finds a positive association between obesity and asthma among south Indian asthmatic subjects.
Key words:-Asthma, BMI, total IgE, obesity, south India. |
Filename | Sudha S et..pdf |
Filesize | 183.76 kB |
Filetype | pdf (Mime Type: application/pdf) |
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Created On: | 06/16/2011 00:00 |
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Last updated on | 07/06/2011 12:39 |
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