Property | Value |
Name | Identification of Myocardial Infarction in Human Autopsy Population Using TTC |
Description | Research article:- Shenoy Revathi P, MSc, PhD 1 , * Bakkannavar Shankar M, MD, DCL 2, Vidya Monnappa, MD, Diplomate NB3, Bhat Akshay V,MSc 4, Mukesh Kumar, MSc,4 Nayak Vinod C, MD 5, Pradeep Kumar G, MD, Dip.Cr.L 6.
1.Assistant Professor, Department of Biochemistry, Kasturba Medical College, Manipal University, Manipal, India. 2.Assistant Professor, Department of Forensic Medicine and Toxicology, Kasturba Medical College, Manipal University, Manipal,India. 3.Associate Professor, Department of Pathology, Kasturba Medical College, Manipal University, Manipal, India. 4.Postgraduate, Department of Biochemistry, Kasturba Medical College, Manipal University, Manipal, India. 5.Associate Professor, Department of Forensic Medicine and Toxicology, Kasturba Medical College, Manipal University, Manipal, India. 6.Professor & Head, Department of Forensic Medicine and Toxicology, Kasturba Medical College, Manipal University, Manipal, India.
Abstract:- Myocardial infarction is the most common cause of sudden death. However the identification of myocardial infarcts at necropsy is difficult. Various methods are being used to detect it. It has been shown that the use of dyes such as nitroblue tetrazolium and 2,3,5 triphenyl tetrazolium chloride (TTC) that identify the dehydrogenase deficient infracted myocardium are largely used. But the studies have been conducted largely in animal models using these dyes. Establishing the utility of these enzyme histochemical tests at autopsy on human cadavers is the need of the hour. We studied the fourty hearts of sudden death cases staining them with TTC and thereafter confirming with histology to know the efficacy of TTC staining. Our results showed that this histochemical test is a reliable method of investigation in sudden death cases.
Key words:- Myocardial infarction, 2,3,5 triphenyl tetrazolium chloride, histochemical tests. |
Filename | M Shankar Bakkannavar et.al..pdf |
Filesize | 237.78 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 08/16/2011 00:00 |
Viewers | Everybody |
Maintained by | Editor |
Hits | 4037 Hits |
Last updated on | 09/04/2011 15:59 |
Homepage | |
CRC Checksum | |
MD5 Checksum |