Property | Value |
Name | A Recent Update on Undeclared Chemicals in Herbal Formulations |
Description | Review article:- Munish Garg, *Monika Hooda, Jyoti Solanki, Sandeep Saini, Sneha Das.
Department of Pharmaceutical Sciences, Maharshi Dayanand University Rohtak, 124001, India.
Abstract:- Adulteration of herbal supplements with undeclared synthetic drugs or by mixing the analogues of prescription can cause a significant risk to public hAealth. Consumers of such adulterated products are at risk of developing serious adverse reactions, potentially leading to pulmonary hypertension, moderate aortic regurgitation, a prominent right heart failure, hypokalemia and even death. These analogues are not declared on the labeling and often created by replacing or adding functional groups to the original chemical. Thus, herbal manufacturers have made it more difficult for the analysts to detect these undeclared pharmaceutical analogues into their products. Although DSHEA has given responsibility to the FDA to enforce guidelines for safety and claims, but as per the regulations, FDA can investigate a supplement only after a safety problem has been reported in a particular formulation thus giving the herbal manufacturers enough courage to launch their unscrupulous products into the market. Therefore, a current need arises to check these practices for the proper quality control of these herbal formulations. In this regard, the enforcement of strict manufacturing guidelines, approval process and quality control conditions may well be a step forward towards the safer use of industrially produced herbal products. Moreover, quality and efficacy of medicinal products should be assessed by randomised clinical trials (RCT) before licenses can be issued.
Key words:- Herbal formulations, quality control of herbals, synthetic adulterants in herbals. |
Filename | Hooda Monika et.al..pdf |
Filesize | 189.05 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 08/16/2011 00:00 |
Viewers | Everybody |
Maintained by | Editor |
Hits | 6833 Hits |
Last updated on | 09/04/2011 16:44 |
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