Property | Value |
Name | Evaluation Of Tinospora cordifolia For Antiurolithiatic Potential |
Description | Research article:- Goyal Parveen Kumar*1(M.Pharm.,PGDPL), Mittal Arun2 (M.Pharm.), Kumar Rishi3 (M.Pharm.)
1.Department of Pharmacology, Hindu College of Pharmacy, Sonepat-131001, Haryana,India. 2.Department of Pharmacognosy, Hindu College of Pharmacy, Sonepat-131001, Haryana,India. 3.Department of Pharmacognosy, IIMT College of Pharmacy, Greater Noida, India-201306.
Abstract: The present study was carried out to investigate the effect of ethanolic extract of Tinospora cordifolia (Wild.) Miers (Family: Menispermaceae) on calcium oxalate crystallization in urolithiasis. Calcium oxalate crystallization was induced by the addition of 0.01M sodium oxalate solutions in synthetic urine. The effect of extract (50, 100, 150, 200 and 250 µg/ml) was studied by time course measurement of turbidity in presence or absence of inhibitor (extract) at 620 nm for ten minutes by means of a spectrophotometer. The comparison between turbidimetric slopes with and without inhibitor gave percentage inhibition of crystallization hence the effectiveness of extract, and by comparing the photomicrographs with and without inhibitor, we concluded that T. cordifolia stem extract remarkably inhibited the calcium oxalate crystal formation hence can be stated to have antiurolithiatic potential.
Keywords:- Urolithiasis, Calcium oxalate, Tinospora cordifolia, Ethanolic extract. |
Filename | Goyal Parveen Kumar et.al..pdf |
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Creator | admin |
Created On: | 08/17/2011 00:00 |
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Last updated on | 09/09/2011 18:34 |
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