Property | Value |
Name | Association between serum copper and tumor markers CEA & CA 125 |
Description | Original research article:- Dr.S.Swaminathan Ph.D1, Ms.Priya Gangadaran M.Sc, M.Phil1, Mr.T.Venkatesh2 Dr.Mitra Ghosh M.D3 1.Biochemistry department, Apollo Speciality Hospital, Chennai -35, India. 2.B.Tech , M.G.R University,Chennai -84, India. 3.Chief of Lab Services, Apollo Speciality Hospital, Chennai -35, India.
Abstract:- Copper is believed to be the switch that turns on the angiogenesis process in tumor cells, by activating the growth factor. Copper is necessary for fetal growth as well as in the production of hemoglobin . This study was undertaken on 40 female patients. in the age group of 16 to 62 years to establish the diagnostics utility of serum copper measurement along with the two tumor markers CEA and CA125. While copper measurement was done using a manual method, CEA and CA125 assays were carried out is fully automatic Roche diagnostic Elecsys 2010 which uses electrochemiluminescence technology. Appropriate quality controls were used to validate the accuracy of the results obtained. Excellent correlation (p<0.0001) between Cu and both the tumor markers were obtained thereby showing a very strong association between serum copper and the two tumor markers. This study concludes that measurement of serum copper along with the two tumor markers will be diagnostically useful in cancer screening / remission.
Key Words:- Copper, CEA, CA 125. |
Filename | Swaminathan S et.al.-2.pdf |
Filesize | 68.7 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 08/17/2011 00:00 |
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Maintained by | Editor |
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Last updated on | 09/09/2011 19:00 |
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