Property | Value |
Name | Drug Prescription Pattern of Antihypertensive Drugs in a Tertiary Hospital |
Description | Research article:- *Torvi. Janaki. R. ( M.D), Hiregouder Narendra.S (D.M)* *Department of Pharmacology,Karnataka Institute of Medical Sciences, Hubli Karnataka, India. Department of Cardiology,Karnataka Institute of Medical Sciences, Hubli Karnataka, India.
Abstract:- Background: Hypertension is a leading contributor to the global burden of all causes of disease, continue its upward growth trends. Poor control of this highly prevalent disease can lead to the development of ischemic heart disease, heart failure, stroke and chronic renal insufficiency. A prescription by a doctor may be taken as a reflection of physician’s altitude to the disease and the role of the drug in its treatment. It also provides an insight into the nature of health care delivery system. Since Blood pressure control is often inadequate even in patients who receive regular care, it has been emphasized that control of hypertension can be better achieved if the processes of care are improved. Materials and Methods: A prospective cross sectional study of 3 months duration was undertaken in the cardiology and medicine out patient department and 240 prescriptions given to the patients with essential uncomplicated Hypertension were collected. Basic drug indications were selected to analyze the prescribing patterns and also to assess the rational prescribing of the drugs. All antihypertensive drug prescriptions, 240 patients of uncompicated hypertension were collected for our sample of hypertension patients of more than 30 years of age. Analysis of data was undertaken using the prescription rate as calculated as the number of prescriptions containing a specific antihypertensive agent divided by the total number of prescriptions. Results and Discussion: Out of 346 prescriptions, there were 208 prescriptions for the newly diagnosed patients and 138 prescriptions for the refill of the newly diagnosed patients during the study period. Out of 208 prescriptions for the newly diagnosed cases. 154 prescriptions contained monotheraphy and 54 prescriptions contained combined therapy. Out of 138 prescriptions for the refill, 84 prescriptions contained monotherapy (6%) and 54 prescriptions contained the combination therapy of antihypertensive agents (39%). Among the monotherapy prescriptions, Beta blockers were the most commonly prescribed and ACE inhibitors the least prescribed. Effective BP control was not achieved in some patients receiving monotherapy. Hence such prescriptions were changed to combination therapy. Conclusion: Hypertension is an important modifiable risk factor. The effective rational therapy of Hypertension is therefore an important primary health care objective in managing and preventing the future serious cardiovascular and renal diseases. This study confirms the quality of prescriptions both in terms of layout and the content of the drugs prescribed. The use of appropriate dose and avoidance of monotherapy prescription with drugs such as the alpha adrenergic agonists reflect the fact that physicians are aware about the importance of the knowledge about the dose response relationship for both beneficial and adverse effects.
Key Words: Antihypertensive Drugs, Prescription Pattern, Uncomplicated Hypertension. |
Filename | Torvi Janaki R et. al..pdf |
Filesize | 55.86 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 08/17/2011 00:00 |
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Last updated on | 09/14/2011 15:29 |
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