Property | Value |
Name | In Vitro Antioxidant Activity of Root Extracts of Pluchea lanceolata |
Description | Research article:- *Surendra Kr. Sharma, N. Goyal. * M. Pharm, Ph. D, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar-125001, Haryana, India. M. Pharm, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar-125001, Haryana, India.
Abstract:-In vitro antioxidant activity of methanolic and aqueous root extracts of Pluchea lanceolata was determined by DPPH free radical scavenging assay and hydrogen peroxide scavenging activity. The extract revealed marked activity as a radical scavenger in a study indicating that extracts have ability to donate hydrogen. The absorption is stoichiometric in respect to the number of electrons taken up. Concentration of 0.1 mg/ml of methanolic extract (PME) and aqueous root extract (PAE) of Pluchea lanceolata exhibited 66.48% and 60.86% DPPH scavenging activity. The antioxidant activity of these extracts towards hydrogen peroxide was also reported. A 88.43% and 79.44% of inhibition of hydrogen peroxide was observed with PME and PAE respectively, when compared with control, at a concentration of 0.1 mg/ml using ascorbic acid as standard and positive control on analysis with UV-Visible Spectrophotometer. The results conclude that the extracts are a potential source of antioxidants of natural origin and may be a candidate for treating pathologies related to free radical oxidation due to its overall antioxidant effect in scavenging free radicals and active oxygen species.
Keywords:- Antioxidant, DPPH, free radical, Pluchea lanceolata, Asteraceae |
Filename | Sharma Kr Surendra et.al..pdf |
Filesize | 201.6 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 09/17/2011 00:00 |
Viewers | Everybody |
Maintained by | Editor |
Hits | 4469 Hits |
Last updated on | 11/24/2011 17:46 |
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