Property | Value |
Name | Antinociceptive and anti-inflammatory activity of Carumbelloside –II isolated from Caralluma umbellata |
Description | Research article:- * Sayantan Ray 1, K.Nagaiah. 2 1* NSHM College of Pharmaceutical Technology, Kolkata, West Bengal, India. 2Organic and Bimolecular Chemistry Division, Indian Institute of Chemical Technology (CSIR), Hyderabad, India.
Abstract: The phytochemical study using Caralluma umbellata (Asclepiadaceae) whole plant allowed the isolation of a pregnane glycoside known as Carumbelloside-II. Carumbelloside-II was evaluated for both antinociceptive and anti-inflammatory activity. The antinociceptive activity was evaluated in acidic acid-induced abdominal constriction test method in Swiss albino mice, while anti-inflammatory activity was evaluated in carrageenan-induced paw edema in Wistar rats. Carumbelloside-II has significant antinociceptive and anti-inflammatory activity. These results of present study confirm the use of Cralluma umbellata traditionally for the treatment of painful and inflammatory condition.
Keywords: Caralluma Umbellata; Asclepiadaceae; Pregnane glycoside; Anti-inflammatory activity, Carumbelloside – II. |
Filename | Ray Sayantan and Nagaiah K.pdf |
Filesize | 194.7 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 12/16/2011 00:00 |
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Maintained by | Editor |
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Last updated on | 01/10/2012 08:57 |
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