Property | Value |
Name | Serum magnesium levels in ischaemic cerebrovascular disorders: a case - control pilot study in north Indian population. |
Description | Original article:- Jaspreet Kaur1, K.M.Prabhu2, L.C.Thakur3. 1Professor,H.O.D.,I.T.S. Centre for Dental Studies and Research, Delhi-Meerut Road, Murad Nagar, Ghaziabad- 201206,India. 2Professor , Department of Biochemistry, 3 Professor , Department of neurology ,UCMS & GTB Hospital, Shahdra, New Delhi, India.
Abstract:- Serum magnesium is an indispensable element for man .It is indispensable activator of over 300 enzymes in humans. Hypomagnesia (ionized form) leads to neuromuscular hyperirritability, tremors, increased vascular resistance ,coronary vasospasm and hypertension . Magnesium deficiency triggers vasoconstriction, enhances vascular endothelial injury and hence leads to atherosclerosis.The present study evaluated serum magnesium levels in transient ischaemic attack and stroke patients. Method: The study was carried on 50 diagnosed cases of acute ischaemic stroke,10 cases of TIA and 60 healthy controls(age and sex matched) Fasting blood samples were collected and assessed for serum magnesium levels. Statistical analysis was performed P value less than 0.05 were considered significant. Result: The value of serum magnesium is significantly lower in patient when compared with controls. Conclusion: Magnesium levels are significantly decreased in ischaemic stroke, though hemorrhagic stroke patients as well as patients of transient ischaemic attack also had magnesium deficiency. Magnesium deficiency predisposes atherosclerosis, the known modifiable risk factor of stroke.
Keywords:- Atherosclerosis, Diabetes mellitus, magnesium, transient ischemic attack, stroke. |
Filename | Kaur Jaspreet et al.pdf |
Filesize | 210.06 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 04/17/2012 00:00 |
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Maintained by | Editor |
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Last updated on | 05/16/2012 08:03 |
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