Property | Value |
Name | Mycological profile of fungal infections from various clinical samples in a tertiary care Hospital |
Description | Original article:- *Narayan Shrihari1, KumudiniT.S D2, Mariraj.J3, Krishna.S3 1MD (Microbiology), Asst. Professor, 2Bact (Microbiology), Tutor, 3Professor,4 Professor and Head, Department of Microbiology, Vijayanagar Institute of Medical Sciences (VIMS), Bellary-583104,India.
Abstract:- Back ground: In recent years, fungi have been emerging more common infection in immunocompromised patients of tertiary care centers. The climate of our country is well suited for a wide varity of fungal infections. Within the limited data available, an increased incidence of invasive candidiasis, aspergillosis and zygomycosis are reported. The infection is commonly observed in patients with uncontrolled diabetes mellitus, newer technologies in medical and surgical therapies, organ transplant, use of invasive devices and broad spectrum antimicrobial agents. Objective: The retrospective analysis for a period three years was undertaken to know the prevalence of common fungal infections in a tertiary care Hospital. Material and Methods: The various clinical samples were collected from the patients presenting with clinically suspected fungal infections. The direct microscopy with potassium hydroxide (KOH) was done to visualize the presence of fungal elements and Gram staining was done for any suspected yeast infection. Fungal culture of all samples were inoculated on two different culture media; one sabourauds dextrose agar (SDA) and the other SDA with chloramphenicol and cycloheximide. Results: A total of 690 clinical samples suspected fungal etiology were included for a period of three years. Out of which corneal scraping was most common sample 478(69.28%), followed by skin scraping 105(15.22%) and nail clipping 50(7.25%). Male to Female ratio of patients is 1.56 and majority of the patients belong to age group 21-50 years. Fusarium species was the predominant fungal isolate 57(22.44%), followed by Aspergillus niger 31(12.20%), Aspergillus flavus 31(12.20%), Aspergillus species 23(9.06%), Aspergillus fumigatus 20(7.87%) and Trichophyton species 20(7.87%). Conclusion: The wet mount preparation of KOH can be used as a screening test for presumptive diagnosis of fungal infections. Laboratory confirmation should be undertaken and fungal infection must be ruled out before prescribing corticosteroids and antibacterial agents.
Keywords:- Candidiasis, aspergillosis and zygomycosis. |
Filename | Shrihari Narayan et al.(5).pdf |
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Creator | admin |
Created On: | 04/17/2012 00:00 |
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Last updated on | 05/19/2012 18:01 |
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