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Name | Assessment of cardiac dysfunction by 2D echocardiography in patients of chronic kidney disease |
Description | Research article:- Rathod Nitin R1, Ghodasara Malay K 2, *Shah Harsh D 3 1MD, Associate professor, Department of internal medicine, 2Resident, MD , 3 Resident, MD , Department of community medicine , Guru Govind Singh Hospital, MP Shah Medical College, Jamnagar, Gujarat , India.
Abstract:- Aim and Objective: To assess the prevalence of systolic and diastolic dysfunction in patients of chronic kidney failure on conservative management. Methods: fifty patients with varying degree of chronic renal failure (CKD) were subjected to two-dimensional M mode echocardiography for determination of systolic and diastolic dysfunction. These included patients with mild to moderate CKD (n =27) and advanced CKD (n = 23). Fifty healthy controls were matched for age and sex. The left ventricular ejection fraction (EF) and fractional shortening (FS) were taken as measures of LV systolic function. Diastolic function was determined by measuring E/A ratio by spectral doppler LV inflow velocity. Results: The mean left ventricular ejection fraction (LVEF) in patients with mild/moderate CKD (56.18 ± 7.36%) and severe CKD (51.17 ± 10%) was significantly lower than the controls (62 ± 5.32%). The mean FS in the three groups was similar, 29.6% patients with mild/moderate CKD and 21.7% patients with severe CKD had FS ≤ 25%. In mild/moderate CKD 51.85% patients and in severe CKD group 82.6% patients had evidence of diastolic dysfunction. The prevalence of left ventricular hypertrophy (LVH) along with systolic dysfunction in severe CKD group was 30.4%, which was significantly higher than mild/moderate CKD group (3.7%). The prevalence of LVH along with diastolic dysfunction in severe CKD group was 56.52%, which was significantly higher than mild/moderate CKD group (11.1%). Conclusion: Patients with chronic kidney disease have higher prevalence of diastolic and systolic dysfunction and diastolic dysfunction appears to occur earlier than systolic dysfunction.
Keywords:-Chronic kidney disease, Cardiac dysfunction, Echocardiography |
Filename | Shah Harsh D et al.pdf |
Filesize | 283.2 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 04/17/2012 00:00 |
Viewers | Everybody |
Maintained by | Editor |
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Last updated on | 05/19/2012 17:59 |
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