Property | Value |
Name | Glycated Hemoglobin and Serum Lipid Profile Associations in Type 2 Diabetes Mellitus Patients |
Description | Original research article:- Samatha P1, *Siva Prabodh V2, Chowdary NVS2, Ravi Shekhar2 1MSC , 2 MD, Dept. of Biochemistry, NRI Medical College and Hospital, Chinakakani, A.P- 522503, India.
Abstract:- Diabetic patients with accompanied (but often unnoticed) dyslipidemia are soft targets of cardiovascular deaths. An early intervention to normalize circulating lipids shown to reduce cardiovascular complications and mortality. Glycated hemoglobin (HbA1c) is a routinely used marker for long – term glycemic control. This investigation is an attempt to evaluate the association between HbA1c and various lipid parameters. Venous blood samples collected from 50 type 2 diabetic patients (26 males, 24 females) and serum analyzed for HbA1c, Fasting blood glucose, Total Cholesterol, Triacylglycerols, HDL-C and LDL-C. L/H risk ratio is also calculated. The levels of HbA1c (%) did not differ significantly between males (8.51 ± 1.17) and females (8.24 ± 1.89), whereas male patients had higher mean values of FBG and various lipid parameters than in females. Patients with HbA1c value >7.0 % showed direct and significant correlation with FBG, TC, LDL-C, L/H risk ratio as compared to patients with HbA1c ≤ 7.0%. There was no significant difference in TG, HDL-C between two groups of glycated hemoglobin. These findings indicate that HbA1c is utilized for screening high risk diabetic patients for early diagnosis of dyslipidemia and timely intervention with lipid lowering drugs.
Keywords:-Diabetes, Dyslipidemia, Glycated hemoglobin, Association. |
Filename | V Siva Prabodh et al.pdf |
Filesize | 494.83 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 04/18/2012 00:00 |
Viewers | Everybody |
Maintained by | Editor |
Hits | 6065 Hits |
Last updated on | 05/23/2012 22:43 |
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