Property | Value |
Name | An evaluation Antimicrobial Activity of Aloe barbadensis Miller (Aloe vera) Gel Extract. |
Description | Original research article:-Microbiology * D.Lalitha Devi1, B.Srinivas2, Bandaru Narasinga Rao 3. 1 Assistant Professor, Dept. of Pharmacology, GSL Medical College, Rajahmundry, A.P., India. 2Tutor in Microbiology, 3Professor & Head, Dept. of Microbiology, Rajivgandhi Institute of Medical Sciences (RIMS) Srikakulam-532 001(AP).,India.
Abstract:- Objective: The present investigation was aimed to examine the antimicrobial activity of Dimethyl sulfoxide (DMSO) crude extracts of Aloe barbadensis Miller (Aloe vera) gel against the selected bacterial and fungal pathogens of Escherichia coli, Klebsiella pnemoniae, Proteus mirabilis, Psedomonas aeruginosa, Staphylococcus aureus, Aspergillus niger , Candida albicans and Penicillium sps. Methods: The bacteria and fungi were identified and confirmed by conventional microbiology techniques and the antimicrobial activity was carried out by standard disc diffusion method against the pathogens by using the crude DMSO extracts of A. vera gel. Results: The antibacterial and fungal activity has been observed in the DMSO gel extracts of A. vera against all the tested bacteria and fungi with varied activity. The maximum zone of inhibition 15mm for E. coli, 13 mm for P. mirabilis, 11mm for Proteus mirabilis and 10 mm for Pseudomonas aeruginosa of Gram Negative and 16 mm for Staphylococcus aureus of Gram Positive bacterial test organisms observed. Similar to antibacterial, the antifungal activity of the A. vera gel extracts also varied according to the concentration. The maximum zone of inhibition 13 mm for C. albicians, 10 mm for Penicillium sps were observed. The A. vera gel extracts were failed to show the zone of inhibition against the A. niger. Conclusion: It is hoped that this study would lead to the establishment of some compounds that could be used to formulate new and more potent antimicrobial drugs of natural origin.
Keywords:- Aloe barbadensisMiller; Aloe vera;; Anti-Bacterial; Anti-fungal; Antimicrobial activity. |
Filename | Bandaru Narasinga Rao et al.(3).pdf |
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Creator | admin |
Created On: | 08/04/2012 00:00 |
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Last updated on | 07/27/2012 16:32 |
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