Property | Value |
Name | Evaluation of trace elements in Hepatitis B |
Description | Research article:-Medical microbiology *Nayakanti Raghu Prakash Reddy1 , Animireddy Kishore2 , A.Franklin3, E.Prabhakar Reddy4 1Assistant Professor of Microbiology, 2Associate Professor of Microbiology,3Professor of Microbiology, 4Associate Professor of Biochemistry, Sri Lakshmi narayana Institute of Medical Sciences, Puducherry, India.
Abstract: Introduction: Viral hepatitis is the inflammation of the liver caused by hepatitis viruses. The most common causes of viral hepatitis are the five unrelated hepatotropic viruses Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D, and Hepatitis E. Zn is essential for normal development and function of cell mediating innate immunity, Selenium is an essential micronutrient for human health, Copper accumulation in fibrotic liver caused by chronic hepatitis may contribute to hepatic injury. Material and Methods: The study was conducted a total number of patients 15 from SLIMS Puducherry, 15 from Arogya diagnostic centre, tirupati, Andhra Pradesh. Collected samples was separated by centrifugation at 2000 rpm for 15 min. Separated samples carried out for assay ie, Zinc, copper, selenium by using standard commercial kits. Results and Discussion: We showed that elevated zinc levels in HBV patients correlate with low levels of AST and ALT. Our study showed that selenium, Zn levels were decreased in HBV Patients. We found serum Zn and selenium, copper levels were decreased comparing with control levels. Conclusion: Zinc and selenium might be considered as a marker of normal liver function. Dietary intake of selenium and Zn are necessary to reduce the liver damage in HBV patients.
Keywords:- Viral hepatitis, Innate immunity, Trace elements, Fibrotic liver. |
Filename | Prakash N R Reddy et al.pdf |
Filesize | 50.91 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 08/04/2012 00:00 |
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Maintained by | Editor |
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Last updated on | 08/02/2012 13:24 |
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