Property | Value |
Name | Chemically Modified Tetracyclines: An Emerging Host Modulatory Therapy |
Description | Review article:-Periodontology and Oral Implantology 1*Sonakshi Gupta and 2 Vidya Dodwad. 1*Postgraduate student (III Yr), Department of Periodontology and Oral Implantology, I.T.S.-CDSR, Muradnagar, Ghaziabad,U.P,India. 2MDS, Professor and Head, Department of Periodontology and Oral Implantology, I.T.S.-CDSR, Muradnagar, Ghaziabad, U.P,India.
Abstract:- Tetracyclines belong to a notable class of biologically active and commercially valuable compounds. Chemically modified tetracyclines are one such group of drugs which have been viewed as potential host modulating agents. A major advantage of CMTs (unlike tetracyclines) is the lack of antimicrobial activity and development of antibiotic resistant microbial flora in vivo in long term therapy. The non-anti-microbial properties of chemically modified tetracyclines (CMTs) have shown a great promise in their therapeutic value in field of dentistry. Among them CMT-1, CMT-3 and CMT-8 have been tested for periodontal applications. Recent studies have shown that CMT-3 and CMT-8 inhibit tumor metastasis and arthritis affected synoviocyte invasion in animal models.
Keywords:- Chemically modified Tetracyclines, Host Modulating agents. |
Filename | Sonakshi Gupta et al.pdf |
Filesize | 107.98 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 08/06/2012 16:36 |
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Maintained by | Editor |
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Last updated on | 08/06/2012 16:39 |
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