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Name | A Prospective study of Pseudomonas aeruginosa and its Antibiogram in a Teaching Hospital of Rural setup |
Description | Research article:-Medical microbilogy *,1B.Srinivas, 2D.Lalitha Devi and 3Bandaru Narasinga Rao. 1 M.Sc (Medical Microbiology), Tutor in Microbiology,3 MD.,Ph.D., Professor & Head, Dept. of Microbiology, Rajivgandhi Institute of Medical Sciences (RIMS), Srikakulam-532 001(AP)., India. 2 Assistant Professor in Pharmacology, Dept. of Pharmacology, GSL Medical college, Rajahmundry, A.P., India.
Abstract: - Background: The objective of our present study was to determine the prevalence of Pseudomonas aeruginosa from various infections and its properties and susceptibility pattern to commonly used antibiotics. Materials and Methods: During a 2-year period, specimens were received from various infections and the same were processed and the Pseudomonas aeruginosa strains isolated using standard microbiological techniques and its properties and antibiogram was studied using 8 antimicrobials. Results: Out of 1810 clinical samples, a total of 168 strains of P. aeruginosa were isolated and the prevalence rate was 9.28%. Maximum number was from samples of pus (55.3%) followed by urine (18.5%). The maximum number of samples from males and the infection was seen maximum among females of age group of 51-60 Yrs.(24.6%) followed by male and female almost equally in the age group of >61Yrs. (21.6% and 22.8% respectively). Fifty six percent of strains produced the pigment pyocyanin(55.35%) followed by Pyoverdin(20.23%). Out 168 strains of Pseudomonas aeruginosa 146 were found Multi Drug Resistant (MDR) strains. Predominant MDR strains isolated from pus 83 (56.85%), urine 24 (16.44%), endo tracheal tubes 16 (10.96%), sputum 10 (6.85%), broncho alveolar lavage 9 (6.16%), ear swabs 4 (2.74%). Pseudomonas aeruginosa has shown resistance to Gentamicin (61.91%), Tobramycin (60.12%), Amikacin (57.74%), Cefixime (88.88%), Ceftazidime (69.64%), Cefoperazone (69.05%), Piperacillin (66.67%), and Carbencillin (41.07%). Conclusion: High prevalence of P. aeruginosa as an opportunistic pathogen has been developing with increased resistance to antimicrobial agents and thus becoming a significant threat.
Key Words:-Pseudomonas aeruginosa, Postoperative wound infections, Prevalence, Nosocomial, Antibiogram. |
Filename | Srinivas ,Lalitha and Narasinga.pdf |
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Creator | admin |
Created On: | 09/04/2012 00:00 |
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Last updated on | 09/18/2012 03:05 |
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