Property | Value |
Name | Validated HPTLC method for simultaneous estimation of Etodolac and Thiocolchicoside in bulk drug and formulation |
Description | Research article:-Quality assurance 1Swapnil W. Tekade, 1Shweta S. Havele, 2*Sunil R. Dhaneshwar. 1Department of Quality Assurance, Bharati Vidyapeeth University, Poona College of Pharmacy, Erandwane, Pune – 411038, Maharashtra, India. 2Department of Pharmaceutical Chemistry, RAK Medical & Health Sciences University College of Pharmaceutical Sciences Ras Al Khaimah Post Box No 11172, U.A.E. Abstract:- This paper describes a new, simple, precise, and accurate HPTLC method for simultaneous estimation of etodolac and thiocolchicoside as the bulk drug and in tablet dosage form. Chromatographic separation of the drugs was performed on aluminum plates precoated with silica gel 60 F254 as the stationary phase and the solvent system consisted of chloroform : methanol : toluene (6 : 2 : 3 v/v/v/v). Densitometric evaluation of the separated zones was performed at 238 nm. The two drugs were satisfactorily resolved with RF values of 0.20 and 0.50 for thiocolchicoside and etodolac, respectively.
Key Words:- Etodolac, thiocolchicoside,HPTLC. |
Filename | Swapnil ,Shweta and Sunil Dhaneshwar.pdf |
Filesize | 223.6 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 10/04/2012 00:00 |
Viewers | Everybody |
Maintained by | Editor |
Hits | 6414 Hits |
Last updated on | 10/10/2012 16:06 |
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