Property | Value |
Name | Antinoceciptive And Anti-inflammatory Activity of Lycopersicon Esculentum( Tomato) On Different Experimental Model |
Description | Research article:-Pharmacology Farhana R1*, Arul Amutha E2, Glory J2, Inbaraj SD2, Muniappan M3. 1Assistant Professor,2Associate Professor,3Professor, Dept. of Pharmacology, Sree Balaji Medical College and Hospital, Chennai, Tamilnadu, India.
Abstract:- Aim: To study the antinoceciptive and anti-inflammatory activity of ethanolic extract of Lycopersicon esculentum Mill, on different experiment models. Materials and Methods: Wister albino rats and Swiss albino mice were used for studying antinoceciptive and anti-inflammatory activity of ethanolic extract of Lycopersicon esculentum at doses 100 mg/kg i.p. and 200 mg/kg i.p. Various models viz. acetic acid induced writhing model (mice), Eddy’s hot plate (rats) and formalin-induced paw licking model (rat) for antinoceciptive study and carrageenin induced paw oedema model (rat) for anti-inflammatory study. Results: In all the models for antinoceciptive study ethanolic extract of Lycopersicon esculentum (100 mg/kg i.p) showed significant decrease in pain sensation when compared to experimental control and standard drug. For anti-inflammatory study, ethanolic extract of Lycopersicon esculentum (100 mg/kg, 200 mg/kg i.p) showed significant decrease in inflammation when compared to control and standard drug. Conclusion: Ethanolic extract of Lycopersicon esculentum showed analgesic (central and peripheral) and anti-inflammatory activity.
Key words:- Antinoceciptive, Lycopersicon esculentum, Formalin test, Anti-inflammatory carrageeni. |
Filename | Farhana R et al.(141-146).pdf |
Filesize | 836.2 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 12/03/2012 00:00 |
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Maintained by | Editor |
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Last updated on | 12/07/2012 08:21 |
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