Property | Value |
Name | Evaluation of the association between the incidences of extended spectrum β-lactamase (ESBL) producing organisms in diabetic patients with recurrent urinary tract infection (UTI) |
Description | Research article:- Microbiology Illamani V, Raveendran SR, Chitralekha S and Menezes GA* Department of Microbiology, Sree Balaji Medical College & Hospital Chromepet, Chennai, India (Bharath University).
Abstract:- Background: Extended spectrum β-lactamase (ESBL) producing organisms lead to various life threatening infections and its prevalence is more common in diabetic patients. The objectives of the study were to study the incidence of ESBL producing organisms in diabetic patients with urinary tract infection (UTI); and to know the common species of ESBL producers in diabetic patients with recurrent UTI. Materials & Methods: A total of 164 patients from both sexes in age group between 30 to 70 years attending diabetic outpatient department (OPD) without any complications, and having symptoms of UTI for more than a week. The study was conducted during June 2011 to June 2012. Results & Discussion: A total of 81 isolates were obtained from these patients. Of these, 19 organisms (11.6% of the total isolates) were found to be ESBL producers; the commonest were Escherichia coli, i.e., 11 isolates (25.6% of total isolates) and Klebsiella pneumoniae, i.e., 4 isolates (20.0% of total isolates). Among these, ESBL producers were found most commonly in patients with recurrent UTI (89.5%). Out of 164 diabetic patients with UTI, 19 patients had ESBL positives organisms in their urine culture. Of which 17 had positive history of recurrent UTI. The present study mainly focuses on the prevalence of ESBL producers among the diabetics with UTI since both diabetes and recurrent UTI is a risk factor for ESBL production. Conclusion: The study shows a strong association of recurrent UTI among patients infected with ESBL producing organisms.
Keywords:- Extended Spectrum β-Lactamase (ESBL), Diabetic patients, Urinary tract infection (UTI).
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