Property | Value |
Name | Oral lichen planus and premalignancy |
Description | Research article:- Oral & Maxillofacial Pathology Manveen Kaur Jawanda1, RV Subramanyam2, Ahmed Mujib B.R.3, Ramesh B Hegde4 , Sampada Kanitker5, Rosy Gupta6 & Chetak Deep Chahal7 .
1Prof & Head, Department of Oral & Maxillofacial Pathology, Luxmi Bai Institute of Dental Sciences & Hospital, Patiala, Punjab. India. 2Prof & Head, Department of Oral and Maxillofacial Pathology, Drs Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Gannavaram, Andhra Pradesh. India. 3Prof & Head, Department of Oral Pathology & Microbiology, Bapuji Dental College & Hospital, Davangere, Karnataka.India. 4Professor, Pramathana Dental care, Bangalore, Karnataka 5Prof. & Head, Department of Oral Pathology & Microbiology, D.Y. Patil Dental college, Sangli, Maharastra. India. 6Oral & Maxillofacial Surgeon, Deakins Mill Way, Egerton, Bolton, UK. 7Dental assistant, Inspire Dental southhall, Southhall, Middlesex, UK.
Abstract: -Objective: A study was conducted to examine biopsy reports of lesions, diagnosed as oral lichen planus, with the hope that a set of parameters could be defined which would be more pathognomonic in diagnosing oral lichen planus, despite the variability of its presentation. Methods & Materials: Fifty histologically diagnosed cases of oral lichen planus were reviewed and were further categorized as oral lichen planus, nonspecific lichenoid stomatitis and lichenoid dysplasia, using well established histological criteria. Results: This study reveals an “Over diagnosis” to the extent of 14% through the inclusion of nonspecific lichenoid stomatitis as well as other conditions, including dysplasia, under the diagnosis of oral lichen planus. So non-uniformity among various pathologists in following the histomorphologic parameters in order to render a diagnosis of oral lichen planus has resulted in significant “Over diagnosis” of oral lichen planus. Conclusions: Aside from the obvious diagnostic errors, such oversight can lead to mistaken impressions concerning the natural behavior of relatively benign process. Hence, an attempt is made for reappraisal of histopathological designation of the lesions that have a lichenoid character.
Keywords:- oral lichen planus, nonspecific lichenoid stomatitis, lichenoid dysplasia, nonspecific lichenoid stomatitis, premalignant lesions, precancerous lesions.
References:- 1.Eisenberg, E. Clinicopathologic patterns of oral lichenoid lesions. Oral & Maxillofacial Surgery Clinics of North America 1994; 6:445-463. 2.Eisenberg, E. & Krutchkoff, D.J. Lichenoid lesions of oral mucosa. Oral Surg Oral Med Oral Pathol 1992; 73:699-704. 3.Hedberg, N., Ng A., & Hunter, N. A semiquantitative assessment of histopathology of oral lichen planus 1986; 15:268-72. 4.Holmstrup, P. The controversy of a premalignant potential of oral lichen planus is over. Oral Surg Oral Med Oral Pathol 1992;73:704-6. 5.Kilpi, A., Rich, A.M., Reade, P.C., & Konttinem, Y.T. Studies of the inflammatory process & malignant potential of oral mucosal lichen planus. Aust Dent J 1996; 41:87-90. 6.Krutchkoff, D.J., Cutler, L., & Laskowski, S. Oral lichen planus: The evidence regarding potential malignant transformation. J Oral Pathol 1978; 7:1-7. 7.Krutchkoff, D.J., & Eisenberg, E. Lichenoid dysplasia: A distinct histopathological entity. Oral Surg Oral Med Oral Pathol 1985; 60, 308-15. 8.Odukoya, O., Gallagher, G., & Shkylar, G. A histologic study of epithelial dysplasia in oral lichen planus. Arch Dermatol 1985; 121:1132-6. 9.Scully, C., & El-Kom, M. Lichen planus: Review & update on pathogenesis. J Oral Pathol 1985; 4:431-58. 10.WHO collaboratory Reference centre for oral precancerous lesions. Definition of leukoplakia & related lesions: An aid to studies on oral precancer. Oral Surg 1978;46:517-39.
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