Property | Value |
Name | A rare case of intraosseous sacral schwannoma |
Description | Research article:- Neurosurgery Lakshmi K1, Santhanam R2*,& Menezes GA1. 1Department of Microbiology. 2Department of Neurosurgery. Sree Balaji Medical College and Hospital, Chennai, India (Bharath University).
Abstract:- Schwannomas are slow-growing, benign tumors derived from schwann cells, the sheath cells that envelop myelinated nerve fibers. Intraosseous schwannomas have been observed, very rarely, in sacrum. We report an intraosseous sacral schwannoma and present the clinical, radiological, histological findings with surgical management and a follow up of 4 years. A 29 year old man presented with pain in the left gluteal region radiating to legs and deteriorating locomotor function. The neurological screening examination revealed no abnormality. The lumbosacral spine X-ray was normal. However, the lumbosacral spine Magnetic Resonance Imaging (MRI) showed a lesion at the S2 level extending from the left S1-S2 to the S3-S4 foramina with scalloping of the S1 and S2 components of the sacrum. Left S1-S3 hemilaminectomy and gross total excision of the tumor was achieved. Histology confirmed an intraosseous schwannoma and the patient’s clinical outcome was good after surgery. No recurrence observed in the 4 years of follow up. Hence diagnosis of such tumor in the earlier stage needs only minimal interventional procedure with better prognosis.
Keywords:- Intraosseous sacral schwannoma, Histology, X-ray, MRI. References:- 1.Fawcett KJ, Dahlin DC. Neurilemmoma of bone. Am J Clin Pathol 1967; 47: 759-66. 2.Samter TG, Vellois F, Shafer G. Neurilemmoma of bone. Report of 3 cases and review of the literature. Radiology 1960; 75: 215-22. 3.Gordon EJ. Solitary intraosseous neurilemmoma of the tibia. Clin orthop 1976; 117: 271-82. 4.Chandhanarat Chandhanayingyong, Apichat Asavamongkolkul, Nittaya Lektrakul and Sorranart Muangsomboon. The Management of Sacral Schwannoma: Report of Four Cases and Review of Literature. Sarcoma 2008; sep 2: doi: 10.1155/2008/845132. 5.Dominguez J, Lobato RD, Ramos A, Rivas JJ, Gómez PA, and Castro S. Giant intrasacral schwannomas: report of six cases. Acta Neurochir (Wien) 1997; 139(10): 954–60. 6.Takeyama Masanobu, Koshino Tomihisa, Nakazawa, Akihiro, et al. Giant Intrasacral Cellular Schwannoma Treated With High Sacral Amputation. Spine 2001; 26(10): E216-9. 7.Guz BV, Wood DP Jr, Montie JE, Pontes JE. Retroperitoneal nerve sheath tumors: Cleveland clinic experience. J Urol 1989; 142: 1434-7. 8.Verstraete KL, Achten E, De Schepper A, Ramon F, Parizel P, Degryse H, et al. Nerve sheath tumors: evaluation with CT and MR imaging. J Belge Radiol 1992; 75: 311-20. 9.Miller PL, Tessler A, Alexander S. Pinck BD. Retroperitoneal Neurilemmoma. Urology 1978; 6: 619-23. 10.Abernathey CD, Onofrio BM, Scheithauer B, Pairolero PC, and Shives TC. Surgical management of giant sacral schwannomas. J Neurosurg 1986; 65(3): 286–95. 11.Pongsthorn C, Ozawa H, Aizawa T, Kusakabe T, Nakamura T and Itoi E. Giant sacral schwannoma: A report of six cases. Ups J Med Sci 2010; 115(2): 146-52. 12.Kotoura Y, Shikata J, Yamamuro T, Kasahara K, Iwasaki R, Nakashima Y, et al. Radiation therapy for giant intrasacral schwannoma. Spine 1991; 16(2): 239–42. 13.Feldenzer JA, McGauley JL, and McGillicuddy JE. Sacral and presacral tumors: poblems in diagnosis and management. Neurosurgery 1989; 25(6): 884–91. 14.Huvos AG and Woodard HQ. Postradiation sarcomas of bone. Health Physics 1988; 55(4): 631–6. |
Filename | Lakshmi K, Santhanam R, & Menezes GA.(311-314).pdf |
Filesize | 943.46 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 01/05/2013 00:00 |
Viewers | Everybody |
Maintained by | Editor |
Hits | 2452 Hits |
Last updated on | 01/07/2013 08:31 |
Homepage | |
CRC Checksum | |
MD5 Checksum |