Property | Value |
Name | Estimation of Microalbuminuria in Type 2 Diabetes Mellitus |
Description | Original article:- A. J. Manjula Devi1 and S.Birundha2* 1Head of the Department & Professor, 2*Post Graduate, Department of Biochemistry, Sree Balaji Medical College, Chennai, India.
Abstract:- Background: Diabetes Mellitus (DM) is a metabolic disorder. Microalbuminuria is the main cause of morbidity and mortality in patients with DM. It is characterized by increased prevalence of arterial hypertension, proliferative retinopathy, and peripheral neuropathy. The present study was undertaken to determine the incidence of Microalbuminuria (Albumin/creatinine ratio) in type 2 diabetic patients. Materials & Methods: 25 patients with diagnosed diabetic subjects were selected for the study. Blood samples were collected for the estimation of FBS (Fasting Blood Sample), serum creatinine and 2 hours post meal for PPBS (Post Prandial Blood Sample). Urine samples were collected in sterilised containers.25 healthy age and sex matched control subjects were chosen. Results: Significant increase in the levels of urine microalbumin was observed in type 2 diabetes compared to healthy controls. Conclusion: Microalbuminuria is the diagnostic marker of nephropathy in diabetes mellitus and is an indicator of microvascular damage affecting renal functions. This study emphasizes the importance of microalbuminuria as an early marker of microvascular morbidity involved in type 2 diabetes and helps in better handling of this pandemic disease, diabetes mellitus. Key words:- Diabetes Mellitus (DM), Microalbuminuria, Diabetic nephropathy.
References:- 1.Dinneen SF, Gerstein HC. The association of microalbuminuria and mortality in non-insulin-dependent diabetes mellitus. A systematic overview of the literature 1997, Jul 14; 157(13):1413-8. 2.Manjunatha Goud B.K et al. Diabetes Mellitus And Microalbuminuria: Factors Affecting collection of urine samples for microalbuminuria.2011, Jan; 2:1. 3.Trinder P. Estimation of glucose by the method of GOD-POD.Clin bio chem. 1969; 6:24. 4.Pedersen LM et al. Screening methods for microalbuminuria in diabetes mellitus.1990, 152(13):912-3. 5.Tietz. Estimation of creatinine by the method of jaffes’s method.Text book of clinical chemistry, 3rd edition,1986;ISBN 0-7216-8886-1 6.Joseph D, Karnoz et al. Screening for a microalbuminuria useful for the testing for the prevention of renal disease in diabetic mellitus.2003; 3:52.
Copyright © 2013 A.J.Manjula Devi and S.Birundha. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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