Property | Value |
Name | Random urine protein to creatinine ratio as an index of renal function and its relation to serum markers |
Description | Original article:- Biochemistry Ms. Revathy.K M.Sc., M.Phil1., Ms.G.Nithya M.Sc2., Dr.Mitra Ghosh M.D3, Dr.S.Swaminathan Ph.D.,FACBI4. 1Technical Supervisor, Department of Biochemistry, 3Director of Medical Sciences, 4Chief of Biochemistry, SRM Institute for Medical Sciences, Vadapalani, Chennai-600 026.India. 2Research Scholar, Department of Medical Biochemistry, Dr.ALM PG IBMS, Tharamani Campus, University of Madras, Chennai-600 113,India.
Abstract:- Laboratory assessment of renal function is one of the most commonly performed tasks in medical practice. A significant number of patients admitted in hospitals have compromised renal function, and the incidence of end stage renal disease (ESRD) is increasing at the rate of 7.5 % each year. The evaluation of renal function should be performed with an understanding of the advantages and shortcomings of available tests. Laboratory tests are useful to guide treatment in patients with established renal insufficiency and to detect subtle renal dysfunction in otherwise healthy individuals. The aim of the study is to find out the association between any two of the six parameters in a group of patients (normal male and female) as well as in some mild renal failure patients, then to pin point which of the two parameter or set of tests most suitable to correctly confirm renal dysfunction. This study also aims to reduce the number of biochemical tests there by reducing the financial burden of renal failure patients. The overall aim is to find out cost effect tests to be used in such cases. A highly significant correlation [p<0.0001] is observed for both serum urea & creatinine with the ratio of urine proteins to creatinine, suggesting that the clinical laboratory needs to measure only 4 analytes, viz serum urea, creatinine and urine proteins & creatinine in a random sample of urine.
Key words:- ARF, CRF, ESRD, Creatinine, Total Protein, Albumin, Calcium, Urine Protein, Urine Creatinine.
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Copyright © 2013 Swaminathan S et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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