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Name | Bacterial Vaginosis and its relation to Preterm birth and fetal outcome |
Description | Research article:- Microbiology M.Bharathi1*,G.Naga Sugeetha2 & I.Jyothi Padmaja3. 1Assistant Professor, 3Professor, Department of Microbiology, 2Tutor, Department of Obstetrics & Gynecology, Andhra Medical College, Visakhapatnam, AP-530002. India.
Abstract: Background: Bacterial vaginosis (BV) is a polymicrobial condition in which normal vaginal flora is replaced by Gardnerella vaginalis and other anaerobic bacteria. In pregnancy BV is associated with increased risk of preterm labor, preterm birth, premature rupture of membranes and other adverse fetal outcomes. Aim: 1. To compare Nugent’s criteria and Amsel’s criteria in the diagnosis of BV. 2. To know whether BV is a risk factor for Preterm delivery. 3. To know the relation between BV and low birth weight. Material & Methods: 60 pregnant women who were in preterm labor with cervical effacement more than 3cm and 60 pregnant women at term labor were included as study and control groups respectively. Swabs were collected from posterior vaginal fornix and BV was diagnosed by Amsel’s and Nugent’s criteria. Statistical Analysis: Standard error of difference between proportions. Results: 37 and 35 pregnant women were nullipara in study and control group respectively. Among study group 37 were below 34wks of gestation (61.6%). BV was diagnosed in 26 and 10 pregnant women by Nugent’s criteria and in 22 and 8 by Amsel’s criteria in study and control group respectively with significant P value ( < 0.05). Babies of low birth weight were born to 55 of pregnant women in study group irrespective of whether they were positive or negative for BV. Conclusions: Nugent’s criteria is superior to Amsel’s criteria in the diagnosis of BV. Bacterial Vaginosis in pregnancy is associated with greater than two fold increased risk of preterm birth and it is not directly related to delivery of low birth weight babies.
Key words: Preterm birth, Nugent’s criteria, Gardnerella vaginalis, Anaerobic bacteria, Adverse fetal outcome.
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Copyright © 2013 M.Bharathi,G.Naga Sugeetha & I.Jyothi Padmaja. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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