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Name | Pharmacognostical and Phyto-Chemical standardization of Pathadi Kwatha: A Polyherbal formulation |
Description | Research article:- Asokan Vasudevan1*,LaxmiPriya Dei2 , Harisha C R3 and V J Shukla4. 1Ph.D. Scholar, 2Associate Prof. & Head, Department of Streeroga and Prasootitantra, 3Head, Pharmacognosy Laboratory, 4Head, Pharmaceutical Chemistry Laboratory, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar,Gujrat, India.
Abstract:- Pathadi Kwatha is indicated in Granthibhuta artava Dushti (one among the eight types of menstrual disorder) characterized by clotted appearance of menstrual bleeding and anovulation with poly cystic ovaries due to Vata-Kapha dushti. Vata-Kaphaja Artava Dushti compared to polycystic ovarian syndrome(PCOS) is characterized by oligomenorrhoea, chronic anovulation, and multiple cystic lesions in either or both the ovaries as evidenced by ultrasonography, with or without obesity, hirsutism, acanthosis nigricans, ultimately leading to Infertility in adult female population. So a new pharmaceutical preparation in the form of Pathadi Kwatha was tried to standardize which is economical in terms of time and machinery usage. Pharmacognostical and phyto-chemical observations revealed the specific characters of all active constituents used in the preparation. For the first time standardization of Pathadi Kwatha was undertaken. The present work was carried out to standardize the finished product Pathadi Kwatha to confirm its identity, quality and purity. The presence of stone cells, sclerates, pitted vessels, simple and compound starch grains, fibres; oil globules embedded in parenchyma cells, were the characteristic features observed in the microscopy of drug combination. Phyto-chemical analysis shows solid content of 7.19% w/w, water soluble extract of 49.52 % w/w, specific gravity of 1.010. On the basis of observations and experimental results, the study may be used as reference standard in the further quality control researches.
Key words:- Pathadi Kwatha, PCOS, Pharmacognosy, Phyto-chemistry.
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Copyright © 2013 Vasudevan Asokan et al.. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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