Property | Value |
Name | Effect of pharmacological agents on orthodontic tooth movement |
Description | Review article:- Orthodontics Gupta Akshay1, Sharma Rakesh2, Kumar Piush3 & Chandra Pavan Kumar4 1PG Student (Orthodontics),2Professor,3Reader,4Professor and Head, Department of Orthodontics &Dentofacial Orthopedics, I.T.S-C.D.S.R, Muradnagar Ghaziabad,India.
Abstract:- Many patients today are taking a range of medications and nutritional supplements that can influence orthodontic treatment. Any pharmacologic agent or supplement consumed by patients can reach the periodontal tissues through the circulation and thus interact with and influence a cell’s response to orthodontic forces. These agents may have the effect of potentiating or inhibiting tooth movement as well as exacerbating or reducing root resorption. Orthodontic treatment is based on the principle that when force is delivered to a tooth and thereby transmitted to the adjacent investing tissues, certain mechanical, chemical, and cellular events take place within these tissues, which allow for structural alterations and contribute to the movement of that tooth. Molecules present in drugs and nutrients consumed regularly by patients can reach the mechanically stressed paradental tissues through the circulation and interact with local target cells. The combined effect of mechanical forces and one or more of these agents may be inhibitory, additive, or synergistic. This article discusses in detail the various drugs that can bring about alterations in the desired orthodontic tooth movement. Keywords:- Paradental tissues, pharmacological agent, periodontal tissues. References:- 1.Masella RS, Meister M. Current concepts in the biology of orthodontic tooth movement. Am J OrthodDentofacialOrthop 2006;129:458-68. 2.Yamasaki K, Miura F, Suda T. Prostaglandin as a mediator of bone resorption induced by experimental tooth movement in rats. J Dent Res 1980;59:1635-42. 3.Sandy JR, Harris M. Prostaglandins and tooth movement. Eur J Orthod 1984;6:175-82. 4.Mohammed AH, Tatakis DN, Dziak R. Leukotrienes in orthodontic tooth movement. Am J Orthod 1989; 95:231-7. 5.Ishnan V, Davidovitch Z. The effect of drugs on orthodontic tooth movement. OrthodCraniofac Res 2006;9:163-71. 6.Arias OR, Marquez-Orozco MC. Aspirin, acetaminophen, and ibuprofen: their effects on orthodontic tooth movement. Am J OrthodDentofacialOrthop 2006;130:364-70. 7.Hellsing E, Hammarström L. The effects of pregnancy and fluoride on orthodontic tooth movements in rats. Eur J Orthod 1991;13:223-30. 8.Igar K, Adachi H, Mitani H, Shinoda H. Inhibitory effect of the topical administration of a bisphosphonate (risedronate) on root resorption incident to orthodontic tooth movement in rats. J Dent Res 1996;75:1644-9. 9.Dolce C, Vakani A, Archer L, Morris-Wiman JA, Holliday LS. Effects of echistatin and an RGD peptide on orthodontic tooth movement. J Dent Res 2003;82:682-6. 10.Collins MK, Sinclair PM. The local use of vitamin D to increase the rate of orthodontic tooth movement. Am J Orthod 1988;94:278-84. 11.Kale S, Kocadereli I, Atila P, Asan E. Comparison of the effects of 1,25 -dehydroxycholecalciferol and prostaglandin E2 on orthodontic tooth movement. Am J Orthod 2004;125:607-14. 12.Kawakami M, Takamo-Yamamoto T. Local injection of 1,25-dihydroxyvitamin D3 enhanced bone formation for tooth stabilization after experimental tooth movements in rats. J of Bone and Mineral Metabolism 2004;22:541-6. 13.Krishnan V, Davidovitch Z. The effect of drugs on orthodontic tooth movement. OrthodCraniofac Res 2006;9:163-71. 14.Shirazi M, Dehpour AR, Jafari F. The effect of thyroid hormone on orthodontic tooth movement in rats. J ClinPediatr Dent 1999;23:259-64. 15.Krishnan V, Davidovitch Z. The effect of drugs on orthodontic tooth movement. OrthodCraniofac Res 2006;9:163-71. 16.Madan MS, Liu ZJ, Gu GM, King GJ. Effects of human relaxin on orthodontic tooth movement and periodontal ligaments in rats. Am J Orthod 2007;131:8.e1-8.10. 17.Soma S, Iwamoto M, Higuchi Y, Kurisu K. Effects of continuous infusion of PTH on experimental tooth movement in rats. J Bone Miner Res 1999;14:546-54. 18.Kalia S, Melsen B, Verna C. Tissue reaction to orthodontic tooth movement in acute and chronic corticosteroid treatment. OrthodCraniofac Res 2004;7:26-34. 19.Shdayfat NB. Effects of drugs on periodontal tissue remodeling and clinical responses to orthodontic mechanotherapy. Pak Oral and Dental J 2011;31:379-88. 20.Karsten J, Hellsing E. Effect of phenytoin on periodontal tissues exposed to orthodontic force--an experimental study in rats. Br J Orthod 1997;24:209-15.
Copyright © 2013 Gupta Akshay et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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