Property | Value |
Name | Neonatal outcome in HIV positive mother |
Description | Research article:- Pediatrics Basavaraj M Patil1*, Sandeep V H2, Harish G3, Venaktesh M Patil4 & Vijayanath.V5 1Associate professor,2Assistant professor,3Resident, Dept of pediatrics, M R medical college, Gulbarga, Karnataka,India. 4Associate Professor, Department of Pharmacology, Navodaya Medical College, Raichur, Karnataka,India. 5Associate Professor, Department of Forensic Medicine & Toxicology, VMKV Medical College & Hospital,Salem, Tamil Nadu,India.
Abstract:- In the present generation it has been established that newborns exposed to mother’s HIV infection have a higher mortality rate than those not exposed. At the same time, some authors have shown that prematurity and low birth weight were considerably associated to morbidity and mortality in the neonatal period as well as in the first year of life. In the present study, 50 HIV seropositive women delivered newborns were considered and followed prospectively and studied the consequences of neonatal outcome in HIV positive mother in terms of mortality, morbidity and somatic growth pattern. The focus of this study is to know the demographic characteristics, load of HIV transmission from mother to child, increase the effectiveness of preventive aspects of HIV regarding mother to child transmission and also to know the neonatal outcome and complications associated. In the present study it was observed that 48% of the seropositive mothers were in the age group of 21 to 25 years most of them were illiterates and housewives. Keywords:- Infection; Mother; Child; Transmission. References:- 1.Temmerman M, Plumer FA, Mirza NB, Ndinya-Achola JO, Wamola IA, Nagelkerke N et al. Infection with HIV as a risk factor for adverse obstetrical outcome. AIDS. 1990; 4 (11):1087-93. 2.Newell ML, Branhmbhatt H, Ghys P. Child mortality and HIV infection in Africa: a review. AIDS. 2004 Jun;18 Suppl 2:S27-34. 3.UNICEF. Les enfants et le SIDA: un désastre imminent; les repercussions croissantes de l’infection à VIH sur les femmes, les enfants et la vie familiale dans le monde en développement. Genève 1990 : 6-8. 4.Monebenimp F, Thio R, Nana AD. Morbidité et mortalité des naissances intra hospitalières du CHU de Yaoundé, Cameroun. Clin Mother Child Health. 2005 ; 2(2) : 355-8. 5.Chase HC. Infant mortality and weight at birth: 1960 United States birth cohort. Am J Public Health Nations Health. 1969; 59: 1618-28. 6.Taha TE, Dallabetta GA, Canner JK, Chiphangwi JD, Liomba G, Hoover DR et al. The effect of human immunodeficiency infection on birth weight and infant and child mortality in urban Malawi. Int J Epidemiol. 1995; 24(5): 1022-9. 7.Braddick MR, Keiss JK, Embree JB et al. Impact of maternal HIV infection on obstetrical and early pregnancy outcome. AIDS, 1990, 4:1001-5. 8.Turner et al. Prenatal Care & Birth Outcome of a cohort of HIV-infected women. Journal of AIDS & Human Retrovirology. 1996 Jul; 12(3):259-67. 9.Stratton el al. (1989-1994) Obstetric K& Newborn Outcomes in a cohort of HIV- infected pregnant women: A Report of the women & Infants Transmission study. Journal of Acquired Immune Deficiency syndromes & I Iuman Retrovirology. 1999 Feb 1 ;20(2): 179-86. 10.Goldstein PJ, Smit R, Stevens M, Sever JL. Association between HIV in pregnancy and antiretroviral therapy, including protease inhibitors and low birth weight infants. Infect Dis Obstet Gynecol 2000; 8: 94-8. 11.Martin et al. Incidence of Premature birth & Neonatal respiratory disease in infants of HIV-positive mothers. Journal of Pediatrics. 1997 Dec; 131 (6):851 -6. 12.Dreyfuss ML, Msamanga GI, Spiegelman D, et al. Determinants of low birth weight among HIVinfected pregnant women in Tanzania. Am J Clin Nutr 2001; 74: 814-26. 13.Minkoff H, Nanda D, Menez R, Fikrig S. Pregnancies resulting in infants with acquired immune deficiency syndrome or AIDS related complex. Obstet Gynecol, 1987, 69:285. 14.Brocklehurst P, French R. The association between maternal HIV infection and perinatal outcome: a systematic review of the literature and meta-analysis. British Journal of Obstetrics and Gynaecology, 1998, 105:839-48. 15.RW Ryder, W Nsa, SE Hassig, F Behetset al: Perinatal transmission of the human immunodeficiency virus type 1 to infants of seropositive woman in Zaire: New England Journal of Medicine Volume 320:1637-42. 16.K. K. Jain, R. K. Mahajan, M. Shevkani and P. Kumar, “Early Infant Diagnosis: A New Tool of HIV Diagnosis in Children,” Journal of Community Medicine 36(2); 2011: 139-42 . 17. Rosemary Spira, Philippe Lepage, Philippe Msellati et al: Natural History of Human Immunodefiency Virus Type 1 Infection in Children: A Five-Year Prospective Study in Rwanda: Journal of American Academy of Pediatrics 104 No. 5 November 1999, p. e56. 18.Miriam Adhikari, Shuaib Kauchali and Anitha Moodley: Clinical Profile and Morbidity Pattern of Infants Born to HIV Infected Mothers in Durban South Africa: Indian Pediatrics 2006;43:804-8. 19.Minkoff H, Nanda D, Menez R, Fikrig S. Pregnancies resulting in infants with acquired immune deficiency syndrome or AIDS related complex. Obstet Gynecol, 1987, 69:285. 20.Dreyfuss ML, Msamanga GI, Spiegelman D, et al. Determinants of low birth weight among HIVinfected pregnant women in Tanzania. Am J Clin Nutr 2001; 74: 814-26.
Copyright © 2013 Basavaraj M Patil et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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