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Name | Effect of Peri-operative vitamin A and vitamin C supplements on type-I tympanoplasty: A clinical study |
Description | Original article:- Mandal Bimal1,Bain Jayanta2*,Das Rina3,Lal Shyam4 & Ahmed Shamshad5
1RMO cum Clinical Tutor,Department of ENT,3Demonstrator,Department of Microbiology, Calcutta National Medical College and Hospital, Kolkata, WB, India. 2Senior Resident, Department of Cardiothoracic & Vascular Surgery, PGIMER & Dr.RML Hospital, New Delhi, India. 4Associate Professor, PGIMES & ESI Hospital, Basidarapore, New Delhi, India. 5Senior Resident, Department of Preventive & Social Medicine, Banaras Hindu University, Varanasi, India.
Abstract:- Background: Type-I tympanoplasty is one of the most common surgery performed by an ENT & Head-Neck surgeon with a variable success rates. An open randomized control study was conducted to evaluate the clinical effect of peri-operative vitamin A and vitamin C supplement in type-I tympanoplasty. Materials & Method: 120 cases of chronic inflammatory middle ear disease with central perforation were selected. Half of them (60 cases, Group-X) received 9 weeks peri-operative vitamin A and C supplements, another 60 cases (Group-Y) patients received placebo. For perforation closure, Type-I tympanoplasty using temporalis fascia was done for all cases. Results: Overall perforation closure was 56 (98.25%) vs 50 (86.21%) [2=5.776, p=0.016] and normal hearing was attained in 50(87.72) vs 30 (51.72%) [2=17.59, p=0.000] between group X and Y. Conclusion: This study suggests that peri-operative supplements of vitamin A and vitamin C can be used to achieve a good clinical success in type-I tympanoplasty.
Key words:- Chronic middle ear disease, Type-I tympanoplasty, Temporalis fascia graft, Vitamin A, Vitamin C.
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Copyright © 2013 Bain Jayanta et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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