Property | Value |
Name | Laboratory diagnostic link between plasma glucose and HbA1c to lipid profile tests |
Description | Original article:-Biochemistry Rajeswari. S 1 M.Sc., Swaminathan. S 2* Ph.D., FACBI , Ebenezer William W 3 M.D. , Kumar J.S 4 M.D., DIP DC (AUS)
Affiliation:- 1Lab Technologist, Biochemistry Department, Central Lab,2Chief of Biochemistry, Biochemistry Department, Central Lab,3Professor & Head , Biochemistry Department, 4Professor, Department of General Medicine , Diabetology In-charge, SRM Medical College Hospital and Research Centre, Kattankulathur, Kancheepuram District 603 203, South India.
Abstract:- Objectives: To find out the laboratory diagnostic link between diabetes and pre cardiac monitoring profile tests. Design/ Subjects: 150 Patients attending the Master Health Check up (MHC), mostly to evaluate their diabetic and cardiac status in our Hospital, comprising of both Men and Women in the age group of 21 to 80 years were enrolled. Plasma glucose, HbA1c and lipid profile tests were measured using state of art instrument and methods to find out the above association. Method: Fasting and Post Prandial samples were collected using standard protocols and plasma Glucose, HbA1c and lipid profile tests were carried out to find out the association between diabetic and cardio vascular disease. The results obtained were subjected to statistical analysis to derive r, t and p values to evaluate the associations. Results: Results of paired t tests with a p value of < 0.001 was considered as significant to conclude an association between the parameters studied. Conclusion: There certainly exists an association between plasma glucose and HbA1c to lipid profile tests and this study recommends that all established diabetic patients should be screened for cardiac related problems. eAG may be introduced as an additional parameter to correlate with HbA1c control. Alternatively, all cardiac patients who bye pass screening for diabetes status should be referred to diabetic clinic for evaluation. Further studies linking other recently developed cardiac markers like Homocysteine, Apolipoproteins, myoglobin, D-dimer etc to diabetic profile tests to further validate the association found in this study using diabetic profile with special cardiac markers.
Key Words:- Diabetes, Lipid Profile, HbA1c, eAG, Cholesterol, HDL-c, LDL-c, VLDL-c, Triglycerides, CVD, CHD.
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