Property | Value |
Name | Study of symptomatic and asymptomatic bacteriuria in antenatal women |
Description | Original article:- Microbiology
T. Karuna1*, K.Vishnuvardhana Rao2,P.Ratna Kumari3 & K. Prabha Devi3**
Affiliation:- *1Department of Microbiology Hi-Tech Medical college & hospital ; Block 3,flat 1,Pandara Rasulgarh, Bhubaneswar ,Odisha, India. 2Associate professor, Department of Microbiology, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences, Chinoutapally, Gannavaram, Krishna Dist. Andhra Pradesh, India. 3Associate Professor, Department of Microbiology, 3**Professor and Head of the Department of Obstetrics and Gynaecology,Siddhartha Medical college and hospital , Vijayawada, Andhra Pradesh, India.
Abstract:- Background: India is a developing country with large population of child bearing age group, majority from low socioeconomic status. Unaware of the possibilities of asymptomatic bacteriuria and its complications and often neglecting minor symptoms due to ignorance, lack of medical facilities; ultimately face antenatal, perinatal and postnatal complications. So present study was taken up at Siddhartha medical college & hospital Vijayawada, Andhra pradesh to know the prevalence of symptomatic and asymptomatic bacteriuria in antenatal women. Material & Methods: We conducted a prospective observational type of hospital based study. A predesigned proforma to take detailed history was designed. Midstream urine samples collected from 500 pregnant women were transported and processed within 1 h. The urine specimens were first tested by screening methods and then processed by quantitative and semiquantitative culture methods. Results: 4.5% symptomatic cases and 9.3% asymptomatic cases showed culture positive bacteriuria. Gram Stain was most sensitive and specific screening method compared with semiquantitative standard loop culture method. Escherichia coli was the most common organism isolated;( 78.5%) in asymptomatic bacteriuria and (66.6%) in symptomatic bacteriuria patients. Nitrofurantoin was the most sensitive drug (77.5%), followed by Cephalexin (67.5%). Prenatal and postnatal complications were more common in noncomplaint asymptomatic bacteriuria patients. Conclusion: All pregnant women should be screened by urine culture, from 1st trimester continuing throughout pregnancy irrespective of socioeconomic status, parity and age. Most antenatal, postnatal and perinatal complications can be prevented by routine screening and treatment.
Key Words:- Antenatal women, Asymptomatic bacteriuria(ASB), Symptomatic bacteriuria(SB).
References:- 1. Lavanya S.V. et al, Asymptomatic bacteriuria in antenatal women,Indian Journal of Medical Microbiology 2002; 2 (20):105-6. 2. Patton JP, Nash DB, Abrutyn E: Urinary tract infection: Economic Consideration, Med. Clin. North Am 1991; 75:495. 3. Mc LaughlinS P, Carson CC, Urinary tract infections in women Medical Clinics of North America, 2004; 88(2):417-29. 4. Kass EH, Pyelonephritis and Bacteriuria: a major problem in preventive medicine. Ann. Int. Med 1962; 56:46-53. 5. Laura A, Schieve, MS, et al Urinary Tract Infection during Pregnancy: It’s association with Maternal Morbidity and Perinatal Outcome. American Journal of Public Health, 1994; 84(3): 405- 10. 6. Gilstrap L.C., 3rd, Ramin S.M. Urinary Tract Infections during Pregnancy, Obstetrics Gynaecology, Clinic of North America 2001; 28(3): 581-91. 7. Mandell G.L., Bennett J.E., et.al. part I, section B, urinary tract infections chapter 66, principles and practice of infectious diseases, 6th edition, volume I, p 875 – 900. 8. F.Gary Cunningham, M.D., et.al.section XII medical and surgical complications in pregnancy, chapter 47, renal and urinary tract disorders, section II, physiology of pregenancy, chaper 8. Maternal adaptation to pregnancy. Williams obstetrics 21 edition, P 1253 – 1258, 186-188, Mc Graw – Hill publisher. 9. Patterson TF, Andriole VT, Detection, Significance and Therapy of Bacteriuria in Pregnancy, Update in the Managed Health care era, Infectious disease Clin. North America 1997; 11(3)593-608. 10. Betty A.forbes, Daniel F.Sahm, et.al, Part –VII diagnosis by organ system, chapter -57, infection of the urinary tract, Bailey and scott’s diagnostic microbiology, 12th edition P 842,855. 11. Mosby publishers. Baron E J, Peterson L R, Finegold S M. Bailey and Scott’s diagnostic microbiology. 9th ed. St. Louis, Mo: Mosby; 1994. pp. 249–257. 12. Hooton TM, Scholees D, Stapleton AE, et al. A prospective study of asymptomatic bacteriuria in sexually active young women. N Engl J Med 2000; 343:992–7. 13.Macejko A.M. et al. Asymptomatic Bacteriuria and symptomatic urinary tract infections during pregnancy; Urologic Clin. N. Am. 34(2007):35-42. 14. Connolly AM et al. Urinary tract infections in pregnancy, Urologic Clinics of North America 1999; 26(4): 779-87. 15. Kutlays et al. Prevalence, detection and treatment of asymptomatic bacteriuria in a Turkish obstetric population, J. Reprod. Med 2003 Aug; 48(8): 627-30. 16. Khattak AM et al. Pakistan Journal of Med. Sci., 2006 ;22(2):162-6. 17. Hanif S, Dept. of Obst & Gynaecology, Fatima Memorial Hospital Collge, Lahore, JCPSP 2006;16(8); 514-7. 18. Bandhopadhyay S, Thakur et al. High prevalence of bacteriuria in pregnancy and its screening methods in north India, Journal Indian Med. Assoc. 2005 May; 103(5): 259-62, 66. 19.Collee J.G.,FraserA.G, et.al. , Laboratory strategy in the diagnosis of infective syndromes,section 11, urinary tract infections chapter 4,Mackie &McCartney practical medical microbiology, 14th edition, p 89 – 90. 20.Mc Fadyer SJ et al. Incidence of asymptomatic Bacteriuria in Primis, The Jour of Obst Gyne of Brit Common Wealth 1973; 5: 80. 21.Jai Bhagawan Sharma, Suneeth Sharma et al. Prevalence of Significant Bacteriuria in Preterm Labour; Jour. Obst.Gyn. Of India 1990; 40(3):336-8. 22. Schieve LA, Handler A, Hershow R, et al. Urinary tract infection during pregnancy: Its association with maternal morbidity and perinatal outcome. Am. J. Public Health, 1994; 84: 405-41. 23. Ian Donald-Practical Obst. Problems, P. 273-77, 1974, PG Publishing Pvt. Ltd., (Publishers). 24. Kincaid-Smith P, Buller M, Bacteriuria in Pregnancy, Lancet 1965; 1: 395-9. 25. F.Gary Cunningham, M.D., et.al.section XII medical and surgical complications in pregnancy, chapter 47, renal and urinary tract disorders, section II, physiology of pregenancy, chaper 8.Maternal adaptation to pregnancy.Williams obstetrics 21 edition, P 1253 –1258, 186-188, Mc Graw – Hill publisher. 26. Eshwarappa M, Dosegowda R, Aprameya IV, Khan MW,Kumar PS, Kempegowda P. Clinico-microbiological profile of urinary tract infection in south India. Indian J Nephrol 2011; 21(1):30-6. 27. Bent S, Nallamothu BK, Simel DL, Fihn SD, Saint S. Does this woman have an acute uncomplicated urinary tract infection? JAMA 2002; 287(20):2701-10. 28. Guinto VT, De Guia B, Festin MR, Dowswell T. Different antibiotic regimens for treating asymptomatic bacteriuria in pregnancy. Cochrane Database of Systematic Reviews 2010, Issue 9. Art. No.: CD007855. DOI: 10.1002/14651858.CD007855.pub2. 29. Vazquez JC, Abalos E. Treatments for symptomatic urinary tract infections during pregnancy. CochraneDatabase of Systematic Reviews 2011, Issue 1. Art. No.: CD002256. DOI: 10.1002/14651858.CD002256.pub2.
*Correspondence address:
Copyright © 2013 Mitul Kumar Mishra & Shilpi Tiwari. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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