Property | Value |
Name | Serum TAU protein levels of stroke patients |
Description | Research article:- Cemil Kavalci1*, Polat Durukan2, Mustafa Burak Sayhan3, Orcun Ciftci4, Yunsur Cevik5, Okhan Akdur6, Gulsum Kavalci7,Ozgur Sogut8 & Omer Salt2.
Affiliation:- 1Baskent University Faculty of Medicine, Emergency Department, Ankara, Turkey. 2Erciyes University Faculty of Medicine, Emergency Department, Kayseri, Turkey. 3Trakya University Faculty of Medicine, Radiology Department, Edirne, Turkey. 4Baskent University Faculty of Medicine, Cardiology Department, Ankara, Turkey. 5Keciören Research and Training Hospital, Emergency Department, Ankara, Turkey. 618 Mart University Faculty of Medicine, Emergency Department, Çanakkale, Turkey. 7Yenimahalle State Hospital, Anesthesialogy Department, Ankara, Turkey. 8Harran University Faculty of Medicine, Emergency Department, Sanliurfa, Turkey.
Abstract: Background and objective: Stroke is the leading cause of death and long-term disability in developed countries. We aimed to study the role of serum tau protein in distinguishing acute hemorrhagic stroke from ischemic stroke, and in the differential diagnosis of sub-types of ischemic stroke. Material and methods: Patients with acute stroke were prospectively enrolled. Serum tau protein levels were assayed. Statistical significance for intergroup differences was compared by Mann-Whitney U test or Kruskal-Wallis test for continuous variables. A p value less than 0.05 was accepted statistically significant. Results and Conclusion: A total of 100 consecutive patients and 20 healthy controls were evaluated. Of the patient group, 29 (29%) had brain hemorrhage on computed tomography and 71 (71%) had ischemic stroke. The median serum tau protein level was 378 pg/mL (90 pg/mL) in hemorrhagic stroke and 482 pg/mL (280 pg/mL) in ischemic stroke, and both were significantly higher compared to controls (p<0.05 for both). There was no significant difference between the ischemic stroke subgroups with respect of median serum tau protein levels (X2=4.258, p>0.05). We suggest that using serum tau protein may be useful to distinguish ischemic stroke from hemorrhagic stroke, but not the ischemic stroke subtypes from each other.
Key Words:- Emergency, Stroke, Tau protein.
References:
Article citation:-
Copyright © 2013 Cemil Kavalci et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
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Created On: | 06/07/2013 00:00 |
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Last updated on | 07/06/2013 05:42 |
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