Original article:-

Maninder Karan*^₁, Kawal Preet ² &  Karan Vasisht³

M. Pharm., Ph. D.*¹, M. Pharm.², M. Pharm., Ph. D.³
University Institute of Pharmaceutical Sciences–UGC Centre for Advanced Studies, Panjab University, Chandigarh 160014, India.

Abstract:-
The present study assessed topical anti-inflammatory activity of different species of an indigenous drug Barleria against croton oil induced oedema in female rats. Seven different extracts viz., mother extract (methanolic, ME, prepared by maceration), hexane (HE), chloroform (CE), ethyl acetate (EAE), butanol (BE) and left aqueous (LAE) extracts obtained after partitioning of ME and total aqueous extract (TAE, prepared by maceration) of each Barleria spp. were evaluated at 200 and 400 mg/ml prepared in croton oil solution using ibuprofen as a standard. The maximum effect was observed at a dose of 200 mg/ml for all the extracts of both the species and chloroform extract of B. prionitis showed the best topical activity with 88.31 per cent inhibition of ear oedema.

Key Words: - Barleria prionitis, B. cristata, Anti-inflammatory, Topical model.

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Article citation:-
Maninder Karan, Preet Kawal & Karan Vasisht. Topical anti-inflammatory studies on Barleria prionitis and B. cristata. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 June; 31(31): 1164-1169.

Copyright © 2013 Maninder Karan, Kawal Preet & Karan Vasisht. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.