DocumentsDate added
Research article:-
* Sayantan Ray1, Noorjaman Rahaman2, Arijit Basu3, Suparna Ghosh Ray4
1Assistant Professor, Department of Pharmaceutical Science, Shivdan Singh Institute of Technology and Management, Aligarh, Uttar Pradesh, India.
2,3Department of Pharmacology, NSHM College of Pharmaceutical Technology, Kolkata, West Bengal, India.
4 Assistant Professor, Department of Radiation Oncology, Burdwan Medical College &Hospital, Burdwan, West Bengal,India.
Abstract: - In the present study, petroleum ether, chloroform and aqueous methanolic extracts of dried leafs of Caralluma fimbriata at the doses of 100 and 200 mg/kg was evaluated for the analgesic activity using the hot plate and acetic acid induced abdominal constrictions in mice. Caralluma fimbriata leaf extract showed significant analgesic properties in all the models studied.
Key Words: Caralluma fimbriata, Analgesic, Hot plate.
Original article:- Gautam Nagori 1 , Rajendra K. Gupta1, Poonam Nagori 2
1 MD, Assistant Professor, Department of Paediatrics,2 MSc Resident, Department of physiology, Jhalawar Medical College, Jhalawar, Rajasthan, India-326001.
Abstract:-
Aim: To identify and co-relate various factors affecting the outcome in children with Scorpion sting envenomation and treatment done by standard protocol using prazosin. Method: This is a prospective study of scorpion sting affected cases in children ( 1-15yrs of age) admitted and treated in dept. of pediatrics , Jhalawar medical college, Rajasthan during the period of January 2010 to December 2011.Permission was taken from Ethical committee of the college before starting the study. Consent was taken from the close relative of the patient. General characteristics of the prazosin. children, anatomic site of the sting, seasonal pattern, clinical and laboratory findings, treatment approaches, complications and outcomes recorded. Result: A total of 61 children of Scorpion sting envenomation admitted in that period. Prevelance of male child’s were found to be 57.3%. Out of them 83.6% cases belongs to rural areas. Extremities were most common site of sting (95%).62% of sting cases occurred in summer months. Local pain, perspiration and cold extremities were seen in almost all cases. The standard treatment followed with the use of prazosin after admission. Mortality seen in only 4.91% of cases. Conclusion: Early hospitalization and administration of accurate dose of prazosin and closely monitoring vitals of the patients in intensive care unit will save many lives.
Keywords:- Scorpion sting envenomation, prazosin, myocarditis, peripheral circulatory failure, pediatric intensive care unit.