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Research article:- Biochemistry
*AKANDE I. S, 1 SAMUEL T. A1 , AGBAZUE .U1 AND OLOWOLAGBA B. L1
1Department of Biochemistry, College of Medicine, University of Lagos, Idi Araba, Lagos, Nigeria.
Abstract:-The comparative nutritive values of different tea brands on sale in Nigeria were investigated and compared with natural Lemon grass extracts. The brands include Lipton tea, Top tea, Nescafe and Green tea. The percentage moisture, ash, crude fibres, lipids and protein contents and antioxidant potentials were evaluated and compared. Phytochemical screening for the various tea brands compared to Lemon grass was also carried out. Results from the study showed that there were significant (p<0.05) differences in the proximate composition of the various tea brands compared with lemon grass . Top tea had the highest percentage of moisture (11.2%), crude fibre (84.35%), lipid (6.09%), protein (0.44%) while Nescafe had the highest percentage of ash content (13.03%). Green tea contained the least ash content (4.79%) while Lemon grass had the lowest percentage lipid (0.42%). Phytochemical screening of these samples revealed the presence of flavonoids, phenolic compounds, glycosides and conjugated dienes in all the four tea brands investigated. Top tea appeared the most balanced nutritionally while the green tea is the most susceptible to rancidity. Data of the study indicate that our indigenous tea brands including the natural extracts of lemon leaf are good sources of antioxidant compounds such as flavonoids, phenolic compounds and glycosides in addition to very few calories and only a small amount of fat with corresponding valuable minerals. They are therefore nutritionally acceptable and medicinally valuable.
Key Words:- Tea, Moisture, Antioxidant, Proximate, Flavonoids, Citrus hystrix.
Research article:-
*,1Dr. Jankana Burana-osot and 2Dr. Wandee Yanpaisan
1Associate Professor, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Silpakorn University, NakhonPathom 73000, Thailand.
2Assistant Professor, Department of Pharmacognosy, Faculty of Pharmacy, Silpakorn University, NakhonPathom 73000, Thailand.
Abstract:- A validated reversed-phase HPLC methodhas been employed for the determination of five individual catechins; (-) epigallocatechin gallate (EGCG), (-) epigallocatechin (EGC), (-) epicatechin gallate (ECG), (-) epicatechin (EC), and (+) catechin (C), and caffeine in green tea simultaneously.The separation was performed on a C18-bonded silica column (4.6 x 250 mm, 5μm) using an isocratic mobile phase comprising of 0.1% acetic acid and methanol (70:30, v/v) with a UV detection at 230 nm. The method validation showed good results for specificity, linearity, precision, accuracy, limit of detection and limit of quantitation. The content of 5 catechins and caffeine in commonly consume green tea brands in Thailand were determined and compared. The resulting data revealed extensive variability in catechins and caffeine amounts. The quantities of EGCG ranged from 5.19 to 58.21, EGC from 2.80 to 52.48, EC from 0.74 to 11.58, ECG from 1.01 to 16.45 and C from 0.09 to 6.10 mg/g of dry tea. Caffeine contents were between 5.81-27.62mg/g of dry tea. EGCG was in the highest concentration in almost tea infusions excepting Japanese green tea, while C was the lowest, excepting Chinese green tea.
Key words:- Green tea, Catechins, Caffeine, HPLC.
Research article:-
Sanjeev Dole1, Amit D. Kandhare2, Pinaki Ghosh2, Tejas P. Gosavi1*, Subhash L. Bodhankar2 1Sanjeeven Homeo Clinic and Research Centre, Pune-411004, Maharashtra, India 2Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Pune-411038, Maharashtra, India
Abstract:- Introduction: Benign Prostatic Hyperplasia (BPH) and Lower Urinary Tract Symptoms (LUTS) are the uprising disease maladies troubling most of the old age population with much distress and irritability. Major surgical procedures without much adverse events gain a popularity of treatment choice. Nevertheless complementary medicine also ranks better in offering the non invasive solution with safety and efficacy. Homeopathy is also one of them frequently prescribed and accepted by the community for relief and cure. Material and Methods: Total 66 men above 40 years were enrolled in this study. All the patients were examined and screened with I-PSS score chart at base line. Three patients with very low and three with very high I-PSS score were excluded from the study. All the patients were followed up for a single time after 15 days from baseline visit. For the same visit the I-PSS score was taken again to compare from initial visit. The homeopathic medicine was prescribed in oral dosage form on 4 globules for a single time. Medicines prescribed on the basis of principle of individualization according to homeopathic philosophy. Result: The I-PSS score and Quality of Life both were found to be improved significantly (P < 0.001) with homeopathic treatment. Conclusion: From the present study it could be concluded that homeopathic treatment is effective therapeutic modality to improve the quality of life and symptomatic relief in men with BPH and LUTS.
Keywords:- Benign prostatic hyperplasia, Homeopathic medicine, International Prostate Symptom Score, Lower urinary tract symptoms, Quality of Life, Questionnaires, Urinary bladder.
Abbreviations:- BPH: Benign Prostatic Hyperplasia, I-PSS: International Prostate Symptom Score, LUTS: Lower Urinary Tract Symptoms, QOL: Quality Of Life.
Research article:-
*Soumendra Sahoo1, Rashmirekha Sahoo2, Yogesh Panditrao Palve 3 and Padmalochan Nayak 3
1Melaka Manipal Medical College, Melaka, Malaysia.
2Nilai University , Nilai, Malaysia.
3P.L.Nayak Research Foundation and Center for Nanoscience and Nanotechnology, Synergy Institute and Technology, Bhubaneswar, Odisha, India.
Abstract:-In the present research program, polymer nanocomposites have been used as the drug carrier for delivery systems of ocular drugs. Tamarind and Polyvinyl Alcohol (PVA) with different ratios were blended with different wt% of Cloisite 30B solution by solvent casting method. Cloisite 30B was incorporated in the formulation as a matrix material component which also plays the role of a co-emulsifier in the nanocomposite preparation. Timolol maleate in different concentrations was loaded with Tamarind-PVA/C 30B nanocomposites for studying the in-vitro drug delivery systems. Morphology and structure characterization of nanocomposites were investigated by fourier transmission infra red spectroscopy (FTIR), scanning electron microscope (SEM), tensile strength and water uptake capacity. The drug release was studied by changing time, pH and drug concentrations. The kinetics of the drug release was studied in order to ascertain the type of release mechanism. Based on the diffusion as well as the kinetics, the mechanism of the drug release from the composite matrix has been reported.
Keywords:-Tamarind, PVA, C 30B, Timolol maleate, Ocular film, Drug Delivery.
Review article:-Periodontology & oral implantology.
Garima Dhariwal 1*, Vidya Dodwad2 & Sweta Kumari Singh3
1Post graduate Student, 2Professor and HOD, 3Post graduate Student, Department of Periodontology & oral implantology, I.T.S. Centre for Dental Studies and Research, Delhi-Meerut Road, Murad Nagar, Ghaziabad- 201206, India.
Abstract:- Chronic inflammatory periodontal disease is caused by host immune responses to periodontal microorganisms. In the past decade, our understanding of the pathogenesis of periodontal disease has improved. As more is learned about the role of the host response, new strategies for periodontal disease management have been emerging.. This development underscores the importance of exploring inflammatory pathways and mediators, thus setting the stage for the development of new prevention and treatment strategies of a widespread disease. So, this review paper discusses components of periodontal disease pathogenesis and their modulation.
Keywords:- Periodontal, Modulation therapies, Host Modulatory therapies.