DocumentsDate added
Research article:-
Soumendra Sahoo1* & Padma Lochan.Nayak 2
1 Melaka Manipal Medical College, Melaka, Malaysia.
2 P.L.Nayak Research Foundation, Centre for Nanoscience and Technology, Synergy Institute of Technology, Bhubaneswar, Odisha ,India.
Abstract:- Chitosan-Gelatin/montmorillonite Cloisite 30 B (MMT) hybrid nanocomposites were prepared by blending chitosan-Gelatin with Cloisite 30B in aqueous solution. The nano composites were characterized by using FTIR, SEM and XRD analysis. From the FTIR spectra the various groups present in the chitosan-Gelatin blend were monitored. The homogeneity, morphology and crystallinity of the blends were ascertained from SEM and XRD data, respectively. The results indicated that an intercalated or partially exfoliated nanocomposite could be achieved, and the properties of the composite were significantly improved. The drug release kinetics was investigated using ketorolac as the drug. The kinetics of the drug delivery system has been systematically studied. Drug release kinetics was analyzed by plotting the cumulative release data vs. time by fitting to an exponential equation which indicated the non-Fickian type of kinetics. The drug release was investigated at different pH medium and it was found that the drug release depends upon the pH medium as well as the nature of matrix.
Key Words:- Chitosan,Gelatin, Cloisite 30 B, Ketorolac, Drug delivery, Kinetics.
References:-
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Copyright © 2013 Soumendra Sahoo & Padma L.Nayak. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
*Correspondence address:
Prof Dr Soumendra Sahoo.,
Head, Ophthalmology,
Melaka Manipal Medical College, Melaka 75150 Malaysia.
Research article:- Forensic Medicine and Toxicology
Shankar M Bakkannavar, MD DCL1, YP Raghavendra Babu, MD2*, Ashwinikumar, MD3, Vinod C Nayak, MD 4, Manjunath S, MD DCL 5, & Pradeep Kumar G, MD, Dip. Cr.L 6.
1Assistant Professor, Department of Forensic Medicine and Toxicology, Kasturba Medical College, Manipal University, Manipal, India.
2Associate Professor, Department of Forensic Medicine and Toxicology, Kasturba Medical College, Manipal University, Mangalore, India.
3Assistant Professor, 4,5 Associate Professor, 6 Professor & Head, Department of Forensic Medicine and Toxicology, Kasturba Medical College, Manipal University, Manipal,India.
Abstract:-
Subendocardial haemorrhage (SEH) is an atypical feature in many forensic autopsies, especially in victims of severe trauma. These haemorrhages are not only accompanied with blood loss due to trauma but also seen in non traumatic conditions such as poisoning and following transfusion of infected blood. In this retrospective study, we have analysed 1778 autopsy cases and investigated for the incidence of subendocardial haemorrhages in relation to their causes.
Key words:-Subendocardial haemorrhage; heart; autopsy; incidence.
References:-
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*Correspondence address:
YP Raghavendra Babu.,
Associate Professor, Department of Forensic Medicine,
Kasturba Medical College, Mangalore - 575001,
Manipal University, Karnataka, India.
Tel : +91 824 2422271(Office), +91 9844884949 (Mobile)
Fax : +91 824 2428183.
Original article:- Microbiology
T. Karuna1*, K.Vishnuvardhana Rao2,P.Ratna Kumari3 & K. Prabha Devi3**
Affiliation:- *1Department of Microbiology Hi-Tech Medical college & hospital ; Block 3,flat 1,Pandara Rasulgarh, Bhubaneswar ,Odisha, India. 2Associate professor, Department of Microbiology, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences, Chinoutapally, Gannavaram, Krishna Dist. Andhra Pradesh, India. 3Associate Professor, Department of Microbiology, 3**Professor and Head of the Department of Obstetrics and Gynaecology,Siddhartha Medical college and hospital , Vijayawada, Andhra Pradesh, India.
Abstract:- Background: India is a developing country with large population of child bearing age group, majority from low socioeconomic status. Unaware of the possibilities of asymptomatic bacteriuria and its complications and often neglecting minor symptoms due to ignorance, lack of medical facilities; ultimately face antenatal, perinatal and postnatal complications. So present study was taken up at Siddhartha medical college & hospital Vijayawada, Andhra pradesh to know the prevalence of symptomatic and asymptomatic bacteriuria in antenatal women. Material & Methods: We conducted a prospective observational type of hospital based study. A predesigned proforma to take detailed history was designed. Midstream urine samples collected from 500 pregnant women were transported and processed within 1 h. The urine specimens were first tested by screening methods and then processed by quantitative and semiquantitative culture methods. Results: 4.5% symptomatic cases and 9.3% asymptomatic cases showed culture positive bacteriuria. Gram Stain was most sensitive and specific screening method compared with semiquantitative standard loop culture method. Escherichia coli was the most common organism isolated;( 78.5%) in asymptomatic bacteriuria and (66.6%) in symptomatic bacteriuria patients. Nitrofurantoin was the most sensitive drug (77.5%), followed by Cephalexin (67.5%). Prenatal and postnatal complications were more common in noncomplaint asymptomatic bacteriuria patients. Conclusion: All pregnant women should be screened by urine culture, from 1st trimester continuing throughout pregnancy irrespective of socioeconomic status, parity and age. Most antenatal, postnatal and perinatal complications can be prevented by routine screening and treatment.
Key Words:- Antenatal women, Asymptomatic bacteriuria(ASB), Symptomatic bacteriuria(SB).
References:-
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*Correspondence address:
Dr. T. KARUNA,
M.D. Microbiology, Assistant professor Department of Microbiology,
Hi-Tech Medical college & hospital; Block 3, flat 1, Pandara, Rasulgarh,
Bhubaneswar, Odisha, India;
Contact no: +91-9437373359.
Copyright © 2013 Mitul Kumar Mishra & Shilpi Tiwari. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article:- Orthopaedics
Anil Salgia, Tushar Agarwal, Sahil Sanghi, Rahul Bagul, Yuvraj & Harshit.
Department of Orthopaedics, Padmashree Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune - 411 018, Maharashatra, India.
Abstract:- Background: - Hospital Acquired Infection defined as infections not present at the time of admission but occurs within hours (clinically evident after 48 hrs) after admission or surgery in a surgical set – up. Aim: - Study the organism and rate of infection in post- op cases. Setting and design: - Department of orthopaedics, Dr. D. Y. Patil Hospital Pune carried a prospective study Material and methods: - Prospective study of 300 post -operative patients was carried out. (14)Patients having discharge on post – operative dressing. 9 cases had discharge from which organism were isolated. Culture and Sensitivity test was done by differential and selective and gram staining. Stastical analysis: - Out of 14 cases, 5 were sterile and 9 were positive (3%). Common organism were Staphylococcus aureus, E.coli ,Klebsiella, Pseudomonas. 4(44.4 %) cases showed Staphylococcus aureus 1(11.11 %) case showed E.coli 2(22.22 %) case showed Klebsiella 1(11.11 %) case showed Pseudomonas 1(11.11 %) case showed mixed (Proteus mirabilis, Streptococcus, Hemolytic Streptococcus). Results: - Post –operative infection rate was 3.0 %. 9 cases were controlled by suitable antibiotic and 2 cases required surgical debribment and implant removal. Commonest organism found were Staphylococcus aureus , E.coli , Klebsiella , Pseudomonas. Conclusion: - Post –operative infection rate was 3.0 %, Infections rate was within limits as given by Centre for Disease Control (CDS) i.e. incidence of 30.2 patients per 1000 patients (3.02 %).
Keywords:-Post–operative,incidence,infections,orthopedics.
References:-
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*Correspondence address:
Dr.Sahil Sanghi,
Department of Orthopaedics,
Padmashree Dr. D. Y. Patil Medical College,
Hospital and Research Centre, Pimpri, Pune - 411 018, Maharashatra, India.
Short review:- Periodontology and Oral Implantology
Singh Preetinder & Kaushal Sumit
MDS, Department of Periodontology and Oral Implantology, Swami Devi Dyal Hospital & Dental College,Barwala,Distt.Panchkula (Haryana) India.
Abstract :- Human tissues harbour stem cells and/or precursor cells which are responsible for tissue development or repair. Recently dental tissues such as Periodontal Ligament, Dental Papilla or Dental Follicle have been identified as easily accessible sources of undifferentiated cells. Dental stem cells could also be feasible tools for dental tissue engineering – a novel approach to treat diseases like periodontitis, dental caries or to improve dental pulp healing and the regeneration of craniofacial bone and teeth. This strategic review gives a short overview of stem cells of dental origin.
Key Words:- Stem cells, Differentiation, Tissue engineering.
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Copyright © 2013 Singh Preetinder & Kaushal Sumit. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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