DocumentsDate added
Review article
Milad Moloudizargari1,*, Shahin Aghajanshakeri1, Soheil Javaherypour1,
Mona Escort1, Salar Velzi2, Sina Velzi2
Affiliation:-
1Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
2Faculty of Veterinary Medicine, Islamic Azad University of Urmia, Iran
The name of the department(s) and institution(s) to which the work should be attributed:
1.Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
2.Faculty of Veterinary Medicine, Islamic Azad University of Urmia, Iran
*To whom it corresponds:-
Milad Moloudizargari.
Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
Email: miladmoludi@gmail.com
Abstract
Yarrow (Achillea millefolium L. family Asteraceae) is a well-known medicinal plant in Iran and various parts of this plant including its flowers have been long used in traditional folk medicine of several cultures, from Europe to Asia. This plant contains a large amount of bioactive compounds that are contributed to a wide range of medicinal properties. Research has revealed different pharmacological and therapeutic effects of A. millefolium and its glycol-alkaloids (particularly achilleine). Studies carried out on the chemical composition of the plant show that the most important constituents of this plant are chamazulene, camphor, sesquiterpene lactones and caryophyllene. In addition to A. millefolium (Asteraceae) achilleine is present in many other plants and is used for the treatment of different diseases. This article reviews the traditional uses and pharmacological effects of total extract and the most active substances of A. millefolium.
Keywords: Achillea millefolium; Yarrow; Achilleine; Pharmacological effects.
Article citation:
Moloudizargari M, Aghajanshakeri S, Javaherypour Soheil, Escort M, Velzi Salar, Velzi Sina. A current update on the phytopharmacological aspects of Achillea millefolium. J Pharm Biomed Sci 2014; 04(04):310-317. Available at www.jpbms.info.
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Moloudizargari M,Aghajanshakeri S,Javaherypour Soheil,Escort M,Velzi Salar,Velzi Sina. This is an open access article distributed under the Creative Commons Attribution
Original article
Panigrahi R1,* Maheshwari A2
Affiliation:-
1Associate professor, 2P.G Student,Department of Otorhinolaryngology, Hi-Tech Medical college and Hospital, Bhubaneswar, Odisha, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Otorhinolaryngology, Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha, India
*To whom it corresponds:-
Dr. Rajlaxmi Panigrahi, M.S.
Associate professor,
Department of Otorhinolaryngology, Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha, India
Contact no:- +91- 09437113636+91- 09437113636
Abstract
Background: Oral submucosal fibrosis (OSMF) is a chronic, crippling condition of oral cavity with a well recognized malignant potential. Its multifactorial etiology and treatment regimes are yet to be standardized. In the present study, the efficacy of combination of triamcinolone acetonide and hyaluronidase has been compared with triamcinolone acetonide alone, given intralesionally at 14 days interval.
Material and method: In a prospective study, patients of OSMF were randomly divided into 2 groups (A and B). Patients in group A received a combination of triamcinolone acetonide and hyaluronidase. Patients in group B received triamcinolone acetonide (1500 IU) alone. In both groups, medication was injected submucosally at 14 days interval, for a total of 8 doses. Treatment outcome was evaluated in terms of improvement in mouth opening and symptom score. Students paired ‘t’ test was used for result comparison.
Result: Patients in group A showed a statistically significant improvement than those in group B. with no complications in either group.
Conclusion: Intralesional injection of combination of triamcinolone acetonide and hyaluronidase is superior to triamcinolone alone, in respect to improvement in symptoms and patient convenience. A follow up study is needed to assess the long term effects.
Keywords: Oral Submucosal Fibrosis [OSMF]; Triamcinolone Acetonide [TA]; Hyaluronidase [HY].
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Article citation:
Panigrahi R, Maheshwari A. A prospective, randomized double blind study comparing intralesional triamcinolone acetonide and hyaluronidase combination versus triamcinolone acetonide alone in the treatment of oral submucosal fibrosis. J Pharm Biomed Sci 2014;04(04):365-370. Available at www.jpbms.info.
Copyright © 2014 Panigrahi R, Maheshwari A. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Sushma Katkuri1,*,Pravinpisudde1,Nithesh Kumar1,Syeda Farha Hasan2
Affiliation:-
1Assistant Professor, Department of Community Medicine, Deccan College of Medical Sciences, Hyderabad,A.P, India
2Final Year MBBS student, Deccan College of Medical Sciences, Hyderabad, A.P, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Community Medicine, Deccan College of Medical Sciences, Hyderabad, A.P, India
*To whom it corresponds:-
Dr Sushma Katkuri*
House No-9 Bhavya Shri Krishna Avenue
Pragati Nagar, Quthbulapur Mandal, Hyderabad-500009, A.P, India
Contact no:-+91- 9160144007
Abstract
A Study to Assess Knowledge, Attitude and Practices of Menstrual Hygiene among School Going Adolescent Girl’s in Hyderabad, India
Background: Adolescent girls constitute a vulnerable group not only with respect to their social status but also in relation to health. Menstruation is regarded as unclean or dirty in Indian society. Although it is a natural process, is linked with several misconceptions and practices which sometimes results into adverse health outcomes. Poor personal hygiene and unsafe sanitary conditions result in the girls facing many gynaecological problems Aims & Objectives: To study knowledge, attitude and practices about menstrual hygiene among adolescent girls. Materials & Methods: A community based cross sectional study was done in school going adolescent girls from a Secondary school near Deccan College of Medical Sciences, Hyderabad. A randomly selected group of 250 adolescents girl’s in the age group of 12 -15 years from class 7th -10th were included in the study. Results: The subjects were maximum in the age group of 13 years (38%) and 14years (37.2%). Almost 54% of the girl’s were aware about the menstrual cycles. 60% reported that mothers were the main source of information about menstrual cycles. Certain faulty practices were followed during menstruation like 54.4 % were not allowed to visit holy places and 45 % said that they are restricted to perform any household activities. Conclusion: The study reflects that the awareness about menstruation was good but still knowledge about certain details regarding menstruation was not known. Therefore the deficiencies can be fulfilled by providing proper information to them by school teachers, health educators and mothers.
Keywords: Adolescents; menstruation; practices; attitudes.
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Article citation:
Sushma Katkuri, Pravin pissude, Nithesh Kumar, Syeda Farha Hasan Abedi. A Study to Assess Knowledge, Attitude and Practices about Menstrual Hygiene Among School Going Adolescent Girl’s in Hyderabad, India. J Pharm Biomed Sci 2014; 04(04):298-302. Available at www.jpbms.info.
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Sushma Katkuri, Pravin pissude ,Nithesh Kumar, Syeda Farha Hasan Abedi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original Article
Bagbi Baribefe M1,* , Omotoso Abayomi E2, Chiagozie Ochuba3
Affiliation:-
1,3Department of Clinical Pharmacy and Experimental Pharmacology, Faculty of Pharmaceutical Sciences, University of Port-Harcourt, Nigeria
2Department of Medicinal and Pharmaceutical Chemistry, University of Port-Harcourt, Nigeria
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Clinical Pharmacy and Experimental Pharmacology, Faculty of Pharmaceutical Sciences, University of Port-Harcourt, Nigeria
Department of Medicinal and Pharmaceutical Chemistry, University of Port-Harcourt, Nigeria
*To whom it corresponds:-
Dr. Bagbi Baribefe M.
Department of Clinical Pharmacy and Experimental Pharmacology, Faculty of Pharmaceutical Sciences, University of Port-Harcourt, Nigeria
Abstract
This study evaluated the quality of seven commercially available (European or Asian sourced) Atorvastatin Calcium(ATV-Ca) tablets products marketed in Southern-Nigeria, with a view to determine their interchangeability in clinical practice. Survey of the assessed Atorvastatin brands was carried out in some southern-Nigeria cities based on their prices. Drug products’ quality assessment included visual examination for their organoleptic properties; tests for weight variation, friability, hardness, disintegration time, dissolution profile and assay for Atorvastatin content. A validated UV-Vis Spectro-photometric method was employed in the assay. Findings indicated that the European sourced samples were 2 to 3 times more expensive than the Asian sourced samples. All brands complied with the official specifications for friability and disintegration time, but sample F failed the test for weight variation (%). Sample C and F also failed the test for tablet hardness. Assay results revealed that with the exception of samples D, F and G, other samples contained >90% (w/w) of labeled potency. Four out of the seven samples attained 70% dissolution within 40min. Comparison of the dissolution profile of the different samples were carried out by model-independent approaches of difference factor(f1), similarity factor(f2) and dissolution efficiency (% DE). These results demonstrated that the European sourced Atorvastatin calcium tablets may after all not be interchangeable with those sourced from Asia.
Keywords: Atorvastatin calcium; Interchangeability; Similarity factor and European.
Article citation:
Bagbi Baribefe M, Omotoso Abayomi E, Chiagozie Ochuba. Comparative Assessment of Quality Brands of Atorvastatin Tablets Marketed in Southern Nigeria. J Pharm Biomed Sci. 2014;04(03):318-326. Available at www.jpbms.info.
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Bagbi Baribefe M, Omotoso Abayomi E, Chiagozie Ochuba. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report:
Banushree C Srinivasamurthy MD DNB, Ambedkar Raj Kulandaivelu MD
Affiliation:-
1Assistant Professor, Department of Pathology & Lab Medicine, AIIMS, Bhubaneswar, India
2Associate Professor, Department of Pathology, Sri Manakula Vinayagar Medical College, Puducherry, India
The name of the department(s) and institution(s) to which the work should be attributed:
1. Department of Pathology & Lab Medicine, AIIMS, Bhubaneswar, India
2. Department of Pathology, Sri Manakula Vinayagar Medical College, Puducherry, India
*To whom it corresponds:-
Dr Banushree CS.
Assistant Professor, Department of Pathology & Lab Medicine, AIIMS, Bhubaneswar, India
Contact no:-+91- 9438884174+91- 9438884174
Abstract
The most common cause of malignant ascites in women is intraperitoneal spread from an ovarian primary carcinoma, usually of the papillary serous type. Occasionally, women with serous borderline tumors present with ascites. Papillary serous neoplasms of the ovary and peritoneum need to be recognized in cytology specimens for appropriate diagnosis and/or staging purposes. Borderline serous carcinoma can go undetectable in intra-operative exploration alone, so cytological examination of peritoneal washings should be done. The distinction of reactive mesothelial cells from serous neoplasms in peritoneal fluids is possible in most patients by cell group architecture and cytological features. We encountered a rare case of borderline papillary serous carcinoma of ovary with presence of malignant cells in peritoneal washing in a forty-three year old female which helped in predicting the behavior and staging of the tumour and establishing proper line of management.
Keywords: Peritoneal washing; reactive mesothelial cells; papillary serous neoplasms; ovary.
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Article citation:
Banushree C Srinivasamurthy, Ambedkar Raj Kulandaivelu. Cytologic identification of borderline papillary serous carcinoma of ovary in peritoneal washing cytology:a case report and review of literature. J Pharm Biomed Sci. 2014; 04(04):279-283. Available at www.jpbms.info.
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Banushree C Srinivasamurthy, Ambedkar Raj Kulandaivelu.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.