Property | Value |
Name | Urine Examination For Determining The Types of Crystals – A Comparative Approach Related to pH |
Description | Original article
Mohamed Marzuk S,Prabhu N.*,Radhakrishna L,Sarada V
Affiliation:- Department of Microbiology, Chennai Medical College Hospital and Research Centre (SRM Group), Tiruchirapalli – 621 105, Tamilnadu, India
The name of the department(s) and institution(s) to which the work should be attributed: Department of Microbiology, Chennai Medical College Hospital and Research Centre (SRM Group), Tiruchirapalli – 621 105, Tamilnadu, India
Address reprint requests to Prabhu N, Ph.D. Department of Microbiology, Chennai Medical College Hospital and Research Centre (SRM Group), Tiruchirapalli – 621 105, Tamilnadu, India
Article citation: Mohamed Marzuk S, Prabhu N, Radhakrishna L, Sarada V. Urine examination for determining the types of crystals – a comparative approach related to pH. J Pharm Biomed Sci. 2014; 04(12):1072-1078. Available at www.jpbms.info
ABSTRACT Background: Studies on the frequency of the different types of urinary crystals and the role of microscopic examination for identification is still uncertain. The analytical complexity of urine particles is largely responsible to understand the pathophysiology of crystal formation. As a result, there is no consensus regarding technical methods in crystalluria with several techniques for urine sampling and three different instruments currently used for particle study, namely particle counting (PC), light microscopy (LM) and petrographic microscopy (PM). Aim: In this work, we first examined urine samples suspected for crystalluria and compared with pH analysis. Settings and Design: We describe the results on the prevalence and typology of crystalluria of the urine samples received in the clinical laboratory of tertiary care rural teaching hospital. Material and Methods: The methodology including the identification of the combined knowledge of crystal morphology with its acidity and alkalinity nature; further confirmation required with infrared spectroscopy and microbial culture analysis. Results and Conclusion: The results highlighted the presence of different types of crystals in the urine samples and strongly supported the pH ranges. The variations in the pH range from 4 to 8. The ratio of 7.5:3.5 was identified among normal and abnormal crystals respectively. Among the normal crystals, calcium oxalate was found in 28% of urine samples and 29% of cystine found among abnormal crystals. The correlation of the results of pH with the crystal formation was well studied and further it gets proved with the theory and reference interpretation.
KEYWORDS: Crystalluria; Calcium oxalate; Cystine; pH ranges; Prevalence.
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Source of support: None
Competing interest / Conflict of interest The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript
Copyright © 2014 Mohamed Marzuk S ,Prabhu N, Radhakrishna L, Sarada V. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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