Property | Value |
Name | PREPARATION AND CHARACTERIZATION TECHNIQUES IN NIOSOMAL VESICULAR SYSTEMS- A REVIEW |
Description | Review article:- Navin K. Dahiya1, *Rekha Rao1, Sanju Nanda2 1.Department of Pharmaceutics, M.M. University, Mullana, Ambala, Haryana, India-133203. 2.Department of Pharmaceutical Sciences, M.D. University, Rohtak, Haryana, India -124001.
Abstract:- Started in 1970’s by cosmetic scientists, the research investigations in the field of niosomal vesicular systems are increasing exponentially with growing interest in these fields. The stream of these vesicles is still in its infancy, but the explosion of interest in niosomes as inherently active therapeutic agents, as vectors for targeted delivery of drugs, peptides and hormones and able to promote oral and transdermal drug delivery makes it timely to review current knowledge regarding various aspects of niosomes. Niosomes are non-ionic surfactant based vesicles formed from the self assembly of non-ionic amphiphiles in aqueous media resulting in closed bilayer structure which can entrap both lipophilic and hydrophilic drugs. The biocompatible and biodegradable nature makes them less toxic as compared to other vesicular systems. Lower cost of niosomes is attributed to greater availability of non-ionic surfactants. These properties make them versatile carriers and interesting candidate for study. The emphasis of this review is on potential of niosomes in drug delivery applications. The composition of niosomes and especially non-ionic surfactants are discussed in detail. Preparation methods are outlined separately for these vesicular systems. In addition, this article concentrates on the success in developing niosomes as potential carriers, in this millennium.
Key words: Non-ionic surfactants, Niosomes, Liposome, Drug delivery. |
Filename | Rao Rekha et al..pdf |
Filesize | 231.73 kB |
Filetype | pdf (Mime Type: application/pdf) |
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Created On: | 04/18/2011 00:00 |
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Last updated on | 04/28/2011 07:14 |
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