Property | Value |
Name | Studies on Fermentation Kinetics for the Synthesis of L-Glutaminase – A Tumour Inhibitor from Microbial Origin |
Description | Research article:- Dhatri Devi. N1, *Siddalingeshwara K.Gurubasappa1, Sunil Dutt P L N S N2, Vishwanatha T3, and Ramesha I3, Jayaramu M4, Dwarakanath V4, Naveen M5 , Sumanth B.K6. 1.Department of Microbiology and Biochemistry Padmashree Institute of Information Sciences, Nagarabhavi, Circle.Bangalore-72, India. 2.Research and Development Centre Bharathiar University, Coimbatore, India. 3.Department of Microbiology and Zoology, Maharani Science college for Women, Bangalore-01.India. 4.Department of Microbiology and Biotechnology, Tumkur University, Tumkur, India. 5.Department of Microbiology, Govt Science College, Bangalore, India. 6.Department of Biotechnology, Kuvempu University. Shankaraghatta, India.
Abstract:- Twenty one Aspergillus wentii isolates were isolated from the soil samples were screened for L-glutaminase synthesis by plate assay method. Among the isolates the potential Aspergillus wentii SD4 were used for the synthesis in elevated level of L-glutaminase by optimizing the fermentation parameters like pH, temperature and inoculums size. The optimized pH will be 5.5 and it showed 1.71 IU. Temperature and inoculums sizes were also optimized as 350C and 1.0 ml (1x107). At this level these parameters shows 2.22IU and 2.73IU in elevated levels.
Key words: Aspergillus wentii, L-glutaminase, Fermentation kinetics, tumour inhibitor. |
Filename | Siddalingeshwara K G et.al.-1.pdf |
Filesize | 175.53 kB |
Filetype | pdf (Mime Type: application/pdf) |
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Created On: | 04/18/2011 00:00 |
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Last updated on | 05/26/2011 17:49 |
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