Property | Value |
Name | Outcome Predictors of Non Traumatic Coma with Infective Etiology in Children |
Description | Original research article:- *Buch Pankaj M1, Parmar Parin2, Doshi Smita K3, Chudasama Rajesh K4.
1M.D. (Pediatrics) ,Professor, Department of Pediatrics, M P Shah Medical College, Jamnagar, Gujarat, India.
2M.D. (Pediatrics) , Assistant Professor, Department of Pediatrics, P D U Medical College, Rajkot, Gujarat, India. 3M.D. (Pediatrics), Professor & Head Department of Pediatrics, P D U Medical College, Rajkot, Gujarat, India. 4M.D. (Community Medicine) , Associate Professor, Department of Community Medicine, M P Shah Medical College, Jamnagar, Gujarat, India.
Abstract:- Objective: To evaluate possible predictors of immediate outcome in non-traumatic coma in children with infective etiology. Method: An observational prospective study was conducted over a period of 15 months from 1st June 2009 to 31st August 2010 at Department of Pediatrics, Government Medical College, Rajkot, Gujarat, India. Children aged 6 months to 12 years presenting with non-traumatic coma with history, clinical features and laboratory studies suggestive of infective etiology were followed upto immediate outcome. A complete history, general and systemic examination at presentation was recorded. Relevant laboratory and radiological investigations were performed and GCS was recorded every 6 hourly until the immediate outcome. The etiology of coma was determined on the basis of history, clinical examination and investigations. Results: CNS infections (n=34), Respiratory tract infections (n=26) and sepsis (n=34) were most common etiology of non traumatic coma. Severe malnutrition and Anemia were comman associated conditions. Thirty Eight (40.4%) survived and Fifty six patients (59.6%) died. survival was better with Meningitis compared to sepsis (p=0.007). GCS <5 on admission, Shock on presentation, Hypothermia, associated severe Malnutrition and significant anemia, Severe dehydration,, abnormal breathing Pattern, Nonreactive Pupils and jaundice correlated significantly with mortality. On logistic regression poor pulse volume, GCS at 24 hrs <5, CNS infection, Jaundice; severe dehydration and significant Anemia were independent significant predictors of death. Conclusion: CNS infections, Respiratory infections and sepsis were most comman cause of non traumatic coma. Shock and Severe Malnutrition contributes to adverse outcome. Simple clinical signs and GCS were good predictors of outcome.
Keywords:- Non-traumatic coma in children, infective etiology, Predictors of mortality. |
Filename | Buch Pankaj M et al..pdf |
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Created On: | 11/16/2011 00:00 |
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Last updated on | 12/17/2011 08:12 |
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