Property | Value |
Name | Screening of Lignosus rhinocerus Extracts as Antimicrobial Agents against Selected Human Pathogens |
Description | Research article:- * Shopana Mohanarji1,2, Sudhahar Dharmalingam1,2, Anandarajagopal Kalusalingam1,2 1School of Pharmacy and Applied Science, La Trobe University, Bendigo, Victoria 3552, Australia. 2Faculty of Pharmacy, Masterskill University College of Health Sciences, Batu 9, Cheras 43200, Selangor, Malaysia.
Abstract:- Over the decades, natural source has become an important essence to discover new antimicrobial compounds to control the dramatic increase of infectious disease. In this present study, petroleum ether, chloroform, methanol, and water extracts of Lignosus rhinocerus sclerotium were obtained. All the extracts were screened for their antibacterial and antifungal activities against gram positive bacteria such as Staphylococcus aureus, Corynebacterium diphtheriae, Bacillus cereus, Stapyhlococcus epidermidis, Streptococcus pyogenes, Strepococcus viridans, Micrococcus luteus, gram negative bacteria such as Klebsiella pneumoniae, Salmonella typhi, Entorobacter aerogenes, Vibro cholera, Escherichia coli, Pseudomonas aeruginosa, Serratia marcescens, Proteus hauseri and fungi such as Candida albicans, Candida tropicalis, Candida krusei and Mucor racemosus by disc diffusion method. Antibacterial and antifungal activities of these extracts were assessed by measuring diameter of zone of inhibition and the results were compared with standard antibiotics, Amoxicillin (10µg/disc) and Fluconazole (30µg/disc) respectively. From these findings, the extracts of Lignosus rhinocerus indicated that plant possess significant antimicrobial activity against tested microbes, which could be a potential source to modern medicine to treat microbial infections.
Keywords:- Lignosus rhinocerus, Mushroom, Antibacterial, Antifungal, Disc diffusion. |
Filename | Mohanarji S. et al.pdf |
Filesize | 104.22 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 05/17/2012 00:00 |
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Last updated on | 06/09/2012 11:47 |
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